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A Registry Collecting Data on Adults With Severe Brain Injury in Intensive Care

Collects health information from adults with severe brain injury to understand recovery.

Plain-language title generated from the registry record
Registry title: The Örebro Severe Traumatic Brain Injury Registry

Key facts

Where
Örebro, SwedenSee the site

Where in Sweden

  • Örebro University HospitalÖrebro, SwedenNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
András Zoltán Buki
Trial code
NCT07398274
Record updated
9 February 2026
Original description
Traumatic brain injury and other severe brain injuries requiring neurointensive care are associated with high mortality, long-term disability and substantial societal burden. Despite advances in critical care, outcomes after severe brain injury remain difficult to predict and secondary brain injury plays a major role in determining prognosis.Read full original descriptionShow less

The Örebro Severe Traumatic Brain Injury Registry (ÖrSBID): A Prospective Observational Cohort Study

Traumatic brain injury and other severe brain injuries requiring neurointensive care are associated with high mortality, long-term disability and substantial societal burden. Despite advances in critical care, outcomes after severe brain injury remain difficult to predict and secondary brain injury plays a major role in determining prognosis.

The Örebro Severe Brain Injury Database (ÖrSBID) is a prospective observational registry that aims to systematically collect detailed clinical, physiological, imaging and biological data from adult patients with severe brain injury requiring care at the neurointesive care unit or neurointermediate care unit at Örebro University Hospital.

The purpose of the registry is to enable deep phenotyping of severe brain injury, improve understanding of secondary injury mechanisms, support outcome prediction and provide a platform for longitudinal follow-up and future research. No experimental interventions are performed as part of the study.

Inclusion: Age > 16 years; Severe traumatic brain injury or other severe brain injury requiring neurointensive or neurointermediate care; Admission to Örebro University Hospital.

Exclusion: Age < 16 years < 90 years; Non-survivable brain injury; Patients not requiring neurointensive or neurointermediate care; Declinced consent by patient or legal representative.

ClinicalTrials.gov NCT07398274