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Measuring Veins' Pressure to Guide Care in Heart Failure

Tests daily vein pressure measurements in adults hospitalized with congestive heart failure.

Plain-language title generated from the registry record
Registry title: Peripheral Venous Pressure (PVP) Trial

Key facts

Where
Milwaukee, United StatesSee the site

Where in United States

  • Aurora St. Luke's Medical CenterMilwaukee, United StatesTaking people

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Trial details

Who runs it
Wake Forest University Health Sciences
Trial code
NCT07400042
Record updated
7 October 2026
Original description
The purpose of the study is to determine if there is a reduction in the length of stay and rates of rehospitalization for patients diagnosed with congestive heart failure when physicians are provided daily measurements of peripheral venous pressure versus no daily measurements of peripheral venous pressure.Read full original descriptionShow less

Reducing the Length of Stay and Incidence of Rehospitalization in Heart Failure Patients by Measuring Peripheral Venous Pressure; a Randomized Clinical Trial

The purpose of the study is to determine if there is a reduction in the length of stay and rates of rehospitalization for patients diagnosed with congestive heart failure when physicians are provided daily measurements of peripheral venous pressure versus no daily measurements of peripheral venous pressure.

Inclusion: Patients with minimum 3-month history of Congestive Heart Failure admitted to Aurora St. Luke's Medical Center with acute decompensation; English speaking only.

Exclusion: Patients who have experienced a major cardiovascular event (myocardial infarction, stroke, etc.) ≤2 months prior to the admission date; Patients who have received an implanted cardiac resynchronization device (pacemaker or ICD) ≤3 months prior to admission date; Patients with current or past vein thrombosis in the arm used to measure the pressure or with history of recurrent (>1) pulmonary embolism; Patients with a clinical condition that the investigator believes may not allow the patient to complete the study, at the discretion of the investigator. Examples of conditions that may apply include severe stenotic valvular disease, isolated right ventricle failure, precapillary pulmonary hypertension, hypertrophic obstructive cardiomyopathy, implanted left ventricular assist device, history of heart transplantation, clinical diagnosis of cardiogenic shock, any left-to-right shunt; Patients with congenital heart disease or mechanical right heart valve(s); Planned heart surgery and/or coronary intervention during hospitalization; Patients expected to receive heart transplant within 6 months of admission; Patients who do not already have a peripheral IV line inserted; Patients whose IV line cannot be transduced; Patients with active thrombophlebitis in the arm; Patients enrolled in other cardiovascular research studies; IV cannula smaller than 22G; Patients who are pregnant and/or lactating; Patients who are unable to provide informed consent; Patients who are intubated.

ClinicalTrials.gov NCT07400042