Studying walking patterns and bone health in spinal muscular atrophy
Looks at how walking patterns relate to bone health in people with spinal muscular atrophy.
Plain-language title generated from the registry record
Registry title: Gait and Bone Health in SMA
Key facts
- Where
- New York, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 8 and 50 years old?
Source: NCT07400198, who can take part
Where in United States
- Columbia University Irving Medical CenterNew York, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Jacqueline Montes
- Trial code
- NCT07400198
- Record updated
- 18 March 2026
- Original description
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT. We hypothesize that gait parameters are associated with BMD and can determine fracture risk in pwSMA. This is an observational study that involves one in-clinic visit (approximately 3 hours) with remote follow-up visits (approximately 15 minutes) every 3 months for 1 year to collect fracture and medical history. Each of the assessments included in this study are non-interventional and are not intended as a treatment nor are they at the level of standard of care.Read full original descriptionShow less
Identification of Gait-related Digital Biomarkers of Bone Health in Spinal Muscular Atrophy
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT. We hypothesize that gait parameters are associated with BMD and can determine fracture risk in pwSMA. This is an observational study that involves one in-clinic visit (approximately 3 hours) with remote follow-up visits (approximately 15 minutes) every 3 months for 1 year to collect fracture and medical history. Each of the assessments included in this study are non-interventional and are not intended as a treatment nor are they at the level of standard of care.
Inclusion: Confirmed diagnosis of 5qSMA; Between 8 and 50 years of age; Able to walk 10 meters without support or an assistive device; All participants who meet the inclusion criteria regardless of treatment status will be included, including those on adjuvant therapies, whether investigational or approved.
Exclusion: Injury or surgery within previous 3 months that would impact ability to perform in-clinic gait assessments; Age less than 8 or over 50 years; Unwilling or unable to comply with all study procedures.