Studying Who Loses Weight After Obesity Medication or Surgery
Studies factors that predict weight loss in adults with obesity receiving medicine or surgery.
Plain-language title generated from the registry record
Registry title: Predicting Weight Loss After Pharmacological or Surgical Treatment in Patients With Obesity
Key facts
- Where
- Brussels, BelgiumSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07402031, who can take part
Where in Belgium
- Cliniques universitaires Saint-LucBrussels, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Université Catholique de Louvain
- Trial code
- NCT07402031
- Record updated
- 14 May 2026
- Original description
As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.Read full original descriptionShow less
Research of Predictive Factors of Weight Loss After Pharmacological or Surgical Treatment in Patients Suffering From Obesity
As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.
Inclusion: Age between 18 and 65 years; Obesity, with bariatric surgery indicated after a multidisciplinary evaluation in case of surgical treatment; Good physical and mental health, enabling informed consent; French speaker.
Exclusion: Recent change in antidiabetic medication within the past 3 months; History of bariatric surgery (except gastric banding, provided it was removed more than five years ago); Acute or progressive chronic disease; Inflammatory bowel disease; Legal protection; Pregnancy or breastfeeding; Alcohol consumption of more than 20 g/day; Digestive autonomic diabetic neuropathy; Consumption of dietary supplements (stanols, probiotics, prebiotics or omega-3); Following a vegan or gluten-free diet or being lactose intolerant; Fibre consumption >30 g/day.