Studying Who Loses Weight After Obesity Medication or Surgery
Studies factors that predict weight loss in adults with obesity receiving medicine or surgery.
Plain-language title generated from the registry record
Registry title: Predicting Weight Loss After Pharmacological or Surgical Treatment in Patients With Obesity
Key facts
- Where
- Brussels, BelgiumSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 65 with obesity who are starting medicine or bariatric surgery for weight loss. It studies what predicts weight loss afterwards.
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Obesity. For surgery, bariatric surgery must be indicated after a multidisciplinary evaluation.
- Earlier treatment
- No earlier bariatric surgery, except gastric banding removed more than five years ago.
Main reasons for not taking part
- Pregnancy or breastfeeding
- Acute or progressive chronic disease
- Alcohol use of more than 20 g/day
- Inflammatory bowel disease or digestive autonomic diabetic neuropathy
- Change in antidiabetic medication within the past 3 months
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07402031, who can take part
Where in Belgium
- Cliniques universitaires Saint-LucBrussels, BelgiumContact: Dr Yannick Deswysen, DoctorTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Université Catholique de Louvain
- Trial code
- NCT07402031
- Record updated
- 14 May 2026
- Original description
As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.Read full original descriptionShow less
Research of Predictive Factors of Weight Loss After Pharmacological or Surgical Treatment in Patients Suffering From Obesity
As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.
Inclusion: Age between 18 and 65 years; Obesity, with bariatric surgery indicated after a multidisciplinary evaluation in case of surgical treatment; Good physical and mental health, enabling informed consent; French speaker.
Exclusion: Recent change in antidiabetic medication within the past 3 months; History of bariatric surgery (except gastric banding, provided it was removed more than five years ago); Acute or progressive chronic disease; Inflammatory bowel disease; Legal protection; Pregnancy or breastfeeding; Alcohol consumption of more than 20 g/day; Digestive autonomic diabetic neuropathy; Consumption of dietary supplements (stanols, probiotics, prebiotics or omega-3); Following a vegan or gluten-free diet or being lactose intolerant; Fibre consumption >30 g/day.