Effect of Combined Quadriceps and Calf Strengthening Program on Gait in Knee Osteoarthritis Patients
Key facts
- Where
- Peshawar, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 60 years old?
Source: NCT07402447, who can take part
Where in Pakistan
- Hayatabad Medical ComplexPeshawar, PakistanContact: Aisha Razzaq, PHD*Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Riphah International University
- Trial code
- NCT07402447
- Record updated
- 9 September 2026
- Original description
The aim of this study is to determine the effects of a combined quadriceps and calf strengthening program on gait, strength, pain, disability, functional mobility, and sleep quality in patients with knee osteoarthritis. A randomized controlled trial will be conducted at Hayatabad Medical Complex, Peshawar. A total of 52 participants aged 40-60 years with grade 2-3 knee osteoarthritis will be recruited using non-probability convenience sampling and randomly allocated into experimental and control groups. Outcome measures include Kinovea software for gait analysis, hand-held dynamometer for strength, Numeric Rating Scale for pain, WOMAC for disability, Timed Up and Go test for function, and Pittsburgh Sleep Quality Index for sleep quality. Data will be analyzed using SPSS version 27 employing repeated measures ANOVA and mixed-way ANOVA.Read full original descriptionShow less
Effect of Combined Quadriceps and Calf Strengthening Program on Gait, Functionality, and Sleep Quality in Knee Osteoarthritis Patients
The aim of this study is to determine the effects of a combined quadriceps and calf strengthening program on gait, strength, pain, disability, functional mobility, and sleep quality in patients with knee osteoarthritis. A randomized controlled trial will be conducted at Hayatabad Medical Complex, Peshawar. A total of 52 participants aged 40-60 years with grade 2-3 knee osteoarthritis will be recruited using non-probability convenience sampling and randomly allocated into experimental and control groups. Outcome measures include Kinovea software for gait analysis, hand-held dynamometer for strength, Numeric Rating Scale for pain, WOMAC for disability, Timed Up and Go test for function, and Pittsburgh Sleep Quality Index for sleep quality. Data will be analyzed using SPSS version 27 employing repeated measures ANOVA and mixed-way ANOVA.
Inclusion: Both Male and Female; Participants aged 40-60years; Diagnosed with grade 2 and 3 of knee osteoarthritis according to Kellgren-Lawrence; Quads manual muscle grading <4; Ability to understand and comply with exercise instructions.
Exclusion: History of recent knee surgery or trauma in the past six months; Inflammatory joint diseases (e.g., rheumatoid arthritis, gout); Severe cardiovascular or neurological disorders; Uncontrolled hypertension or diabetes; Cognitive impairment or inability to follow commands; Participation in other physiotherapy or pharmacological interventions for knee OA during the study period.