A computer alert to help emergency departments find hepatitis C infection
Tests a computer alert that flags emergency patients at high risk of hepatitis C.
Key facts
- Who runs it
- University of Florida
- Where
- Gainesville and Jacksonville, United StatesSee the 3 sites
- Trial code
- Registry title
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System
- Status
- Not yet recruiting
- People taking part
- 6,466 people, planned
- Started
- 1 Jul 2026
- Expected to end
- Jul 2027
- Type of study
- Observational, 3 groups
- Treatments tested
- Physician-Initiated Screening (Conventional Screening)
- FOCUS (Universal Screening)
- HepC-EnD (Targeted Screening)
- Record updated
- 29 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 79 who come to the emergency department. It tests a screening tool that flags people at high risk of hepatitis C.
- Age
- 18 to 79 years
- Sex
- All sexes can join.
Main reasons for not taking part
- Younger than 18 years
- Medically unstable
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- 18-79 years of age
Who cannot take part
- < 18 years of age
- Medically unstable
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 79 years old?
Where in United States
- UF Health Shands Emergency Room / Trauma CenterGainesville, United StatesContact: Haesuk Park, PhDNo longer taking part
- UF Health Jacksonville Emergency RoomJacksonville, United StatesContact: Haesuk Park, PhDNo longer taking part
- UF Health North Emergency RoomJacksonville, United StatesContact: Haesuk Park, PhDNo longer taking part
About the trial
What the trial wants to find out
The goal of this observational study is to develop, implement, and evaluate a machine learning algorithm-based Hepatitis C Emergency Department (HepC-EnD) screening tool for use in emergency departments (EDs) to identify patients at high risk of hepatitis C virus (HCV) infection. HepC-EnD will be integrated into the University of Florida Health electronic health record (EHR) system as a best practice alert (BPA) pop-up for ED providers, notifying them of patients at high risk for HCV infection and recommending both HCV and human immunodeficiency virus (HIV) screening. Investigators aim to enhance the screening and diagnosis of individuals who may otherwise remain undiagnosed and untreated.
Read full original descriptionShow less
The implementation outcomes (e.g., usability) and effectiveness outcomes (e.g., HCV screening and diagnosis rates) of HepC-EnD targeted screening will be compared with universal screening (FOCUS) and conventional physician-initiated screening programs in EDs.
The 3 groups in the trial
- UF Jacksonville North ED
Patients presenting to UF Jacksonville North ED who opt-in for HCV screening during nurse triage.
Treatment: FOCUS (Universal Screening)
- UF Jacksonville Downtown ED
Patients presenting to UF Jacksonville Downtown ED who opt-in for HCV screening during nurse triage (pre- and post-implementation).
Treatment: FOCUS (Universal Screening) and HepC-EnD (Targeted Screening)
- UF Gainesville ED
Patients presenting to UF Gainesville ED (pre-implementation) and patents presenting to UF Gainesville ED who opt-in for HCV during nurse triage (post-implementation).
Treatment: Physician-Initiated Screening (Conventional Screening) and HepC-EnD (Targeted Screening)
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System
- Plain-language title
- A computer alert to help emergency departments find hepatitis C infectionGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07406490, who can take part
- Record updated
- 29 April 2026