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Two Types of Machine-Based Strength Training in Women With Obesity Who Are Inactive

Compares two kinds of strength training over 8 weeks in inactive women with obesity.

Plain-language title generated from the registry record
Registry title: Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations

Key facts

Where
Kepala Batas, MalaysiaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 45 years old?

Source: NCT07407621, who can take part

Where in Malaysia

  • Department of Community HealthKepala Batas, MalaysiaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Universiti Sains Malaysia
Trial code
NCT07407621
Record updated
12 February 2026
Original description
The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is:Read full original descriptionShow less

Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations Among Obese, Untrained Women

The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is:

1. Does exercise-induced neuromuscular adaptation following progressive short ECC ISO RT, more effectively than CON ISO RT, among obese, untrained women?

Researchers will compare drug ECCISO RT to a CONISO RT to see if ECCISO RT is more effective in inducing neuro-muscular adaptations in obese, untrained women.

Participants will:

1. Train on isokinetic ECC or CON for 8 weeks 2. Visit the clinic twice for baseline and post tests

Inclusion: Eumenorrheic women (reporting menstrual cycle between 21-35 days); Age 25-45 y/o; BMI > 23.0 kg/m2; Body fat percentage > 30%; No lower limb orthopaedic injuries; Have not participated in any structured/ unstructured weight loss intervention in the past 12 months; Sedentary lifestyle (regular exercise <1 hour per week); Stable body weight (loss or gain of no greater than 2 kg); Stable medication use for six months before enrolment.

Exclusion: taking supplements or medication known to affect REE (such as oral contraceptives); suffer from alcohol or drug abuse; severe medical conditions affecting their physical or mental health; smokers; individuals with an implanted medical device; trying to conceive/ pregnant, or breastfeeding.

ClinicalTrials.gov NCT07407621