A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs
Key facts
- Where
- Chicago, Los Angeles, and New York, United StatesSee the 3 sites
Where in United States
- The University Of ChicagoChicago, United StatesNo longer taking part
- University of Southern CaliforniaLos Angeles, United StatesNo longer taking part
- NYU Langone HealthNew York, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- NYU Langone Health
- Trial code
- NCT07409350
- Record updated
- 10 November 2026
- Original description
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk Project (TSP), followed by a Hybrid Type II cluster randomized trial of the LINKED intervention (versus an equal-attention control) among N=372 people who inject drugs, with 6- and 12-month follow-up assessment of PrEP and MOUD uptake. The investigators will also evaluate implementation outcomes to inform future sustainable implementation of LINKED in harm reduction organizations.Read full original descriptionShow less
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk Project (TSP), followed by a Hybrid Type II cluster randomized trial of the LINKED intervention (versus an equal-attention control) among N=372 people who inject drugs, with 6- and 12-month follow-up assessment of PrEP and MOUD uptake. The investigators will also evaluate implementation outcomes to inform future sustainable implementation of LINKED in harm reduction organizations.
Inclusion: Aim 1 - Virtual Focus Group; Is 18 years or older; Is a current TSP staff; Is capable and willing to provide consent; Aim 2 - Intervention; 18 years or older; Spend majority of their time in the Los Angeles, CA area where recruited; Able to complete surveys and group sessions in English; Self-report to have injected drugs in the past 3 months; Self-reported HIV negative serostatus; Not currently on PrEP or MOUD; Not pregnant; If a network recruit: presents a valid recruitment coupon; Is capable and willing to provide consent; Aim 3 - Virtual Focus Group/Surveys; Is 18 years or older; Is a current TSP staff; Is capable and willing to provide consent.
Exclusion: Does not self-report injecting drugs in past 3 months; Currently on PrEP or MOUD; Self-reported HIV positive serostatus; Under age 18; Aims 1 and 3:; Individuals who are not current TSP staff members will be excluded from participation; Aim 2:; Does not spend majority of time in the Los Angeles, CA area where recruited; Unable to complete surveys and groups sessions in English; Currently pregnant; If a network recruit: does not present a valid recruitment coupon.