How Thyroid Hormone Changes Affect Blood Sugar in Graves' Disease and Thyroid Cancer
Studies how lowering or raising thyroid hormone affects blood sugar and fat handling.
Plain-language title generated from the registry record
Registry title: Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
Key facts
- Where
- Ulm, GermanySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people newly diagnosed with Graves' disease or thyroid cancer, whose thyroid hormone levels are changed by treatment.
- Sex
- All sexes can join.
- Disease stage
- Initial (first) diagnosis of Graves' disease or of thyroid carcinoma.
Main reasons for not taking part
- Reasons that rule out an oral glucose tolerance test
- Diabetes mellitus
- Fasting glucose level of 200 mg/dL (11.1 mmol/L) or higher
- Insulin injections still acting at the time of the test
- Acute infectious disease
Read by machine on 12 November 2026.
Where in Germany
- Ulm University HospitalUlm, GermanyContact: Roza Sabia, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Ulm
- Trial code
- NCT07410637
- Record updated
- 13 February 2026
- Original description
The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism.Read full original descriptionShow less
Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism.
Patients will be included in whom thyroid hormone levels are intentionally changed by treatment. In patients with Graves' disease, thyroid hormone levels will be lowered using medication, while in patients with thyroid cancer, thyroid hormone levels will be raised using medication. Oral glucose tolerance tests will be performed before treatment and at two time points after treatment begins to assess metabolic effects.
Inclusion: patients with initial diagnosis of graves disease OR; patients with initial diagnosis of thyroid carcinoma.
Exclusion: Diabetes mellitus; Current disease with activation of stress hormones; Acute infectious disease; contraindications for oral glucose tolerance test; Fasting glucose level ≥ 200 mg/dL; Exogenous insulin administration with action at the time of the test; Post-aggressive metabolism.