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CompletedNo phase

Dexmedetomidine vs Midazolam in Coronary Artery By-pass Surgery

Key facts

Who runs it
Cumhuriyet University
Where
Türkiye1 site in 1 countryChoose a country to see its sites
Trial code
Status
Completed
People taking part
50 people enrolled
Started
15 Jan 2026
Ended
2 Jun 2026
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Intravenous Dexmedetomidine infusion + Standard Anesthesia
  • intravenous midazolam infusion + Standard anesthesia
Record updated
4 June 2026

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 6 criteriaShow less

Who can take part

  • Adult patients scheduled for elective coronary artery bypass graft surgery

Who cannot take part

  • Patients with renal disorders,
  • Patients with hepatic disorders,
  • Patients with neuropsychiatric disorders,
  • Patients whom informed consent could not be obtained
  • Patients who declined to participate in the study

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The aim is to compare the incidence of postoperative delirium following coronary artery bypass grafting (CABG) between patients receiving dexmedetomidine and those receiving midazolam infusions.

The 2 groups in the trial

  • DexmedetomidineExisting treatment, for comparison

    Following the induction of standard general anaesthesia, dexmedetomidine will be administered as a continuous intravenous infusion at a dose of 0.3-0.7 µg/kg/h.

    Treatment: Intravenous Dexmedetomidine infusion + Standard Anesthesia

  • MidazolamExisting treatment, for comparison

    Following the induction of standard general anaesthesia, midazolam will be administered as a continuous intravenous infusion at a dose of 0.03-0.06 mg/kg/h.

    Treatment: intravenous midazolam infusion + Standard anesthesia

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
A Comparative Evaluation of Dexmedetomidine and Midazolam ınfusions With Respect to Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting
Record updated
4 June 2026