HeartLogic Alerts to Guide Medicine Choices in Heart Failure With Low Ejection Fraction
Tests HeartLogic alerts alongside usual care in adults with chronic heart failure.
Plain-language title generated from the registry record
Registry title: Evaluation of the HeartLogic Diagnostic in Optimizing Guideline-directed Medical Therapy in Patients With Congestive Heart Failure and Chronically Low Ejection Fractions (EFs)
Key facts
- Where
- Indianapolis and Nashville, United StatesSee the 2 sites
Where in United States
- Ascension St. Vincent Medical GroupIndianapolis, United StatesNo longer taking part
- Saint Thomas Heart at Saint Thomas MidtownNashville, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Robert Pickett
- Trial code
- NCT07412626
- Record updated
- 17 February 2026
- Original description
The goal of this trial is to determine if the addition of the Heart Logic diagnostic alerts to standard of care therapies will lessen hospitalizations and improve quality of life in patients with heart failure.Read full original descriptionShow less
HeartLogic Optimization of CHF Medications in Chronic Low EF Population: A Follow-on Study
The goal of this trial is to determine if the addition of the Heart Logic diagnostic alerts to standard of care therapies will lessen hospitalizations and improve quality of life in patients with heart failure.
Inclusion: Age 18 years or older; EF </=35%; Prior hospitalization within the last two years or prior decompensation to NYHA class III or IV over the last 12 months that was treated without hospitalization; HeartLogic capable ICD or CRT-D (Patients with HeartLogic capable ICD or CRT-D can be enrolled at time of de novo implantation or generator change out or at the time of the 2 week wound check. Prior Heart logic capable ICF or CRT-D implants can be enrolled if heart failure hospitalization shows decompensation within six months (prior implants must have at least 1 year battery life).
Exclusion: Documented noncompliance that limits medication use; Patients on Dialysis (renal insufficiency but not on dialysis is NOT an exclusion); Refuse to give consent; Have Life expectancy of less than one-year; Pregnancy.