Why the Size of Liver Tumor Heat Treatment Varies from Person to Person
Looks back at microwave ablation of liver tumors and what changes the treated area.
Plain-language title generated from the registry record
Registry title: Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors
Key facts
- Where
- Vandœuvre-lès-Nancy, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 100 years old?
Source: NCT07413640, who can take part
Where in France
- CHRU NancyVandœuvre-lès-Nancy, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Central Hospital, Nancy, France
- Trial code
- NCT07413640
- Record updated
- 21 October 2026
- Original description
Microwave ablation is a minimally invasive technique whose planning relies on manufacturer tables derived from ex vivo models that do not account for patient or tumor-specific factors. In clinical practice, the actual ablation volume often differs from the planned volume due to liver characteristics, vascular proximity, and tumor biology.Read full original descriptionShow less
Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors : a Retrospective Study
Microwave ablation is a minimally invasive technique whose planning relies on manufacturer tables derived from ex vivo models that do not account for patient or tumor-specific factors. In clinical practice, the actual ablation volume often differs from the planned volume due to liver characteristics, vascular proximity, and tumor biology.
This study aims to assess the variability between ablation small axis during percutaneous microwave ablation of liver lesions. The influence of patient-related (fibrosis, steatosis, portal flow) and tumor-related factors (location, histology, prior treatment) will be evaluated. Small axis and volume will be compared with volumes measured on immediate post-procedural CT and on CT/MRI at 6-12 weeks, accounting for expected tissue shrinkage.
Inclusion: Adult patients; Treated with percutaneous hepatic microwave ablation under CT or ultrasound guidance; Adult treated for one or more liver lesions; Patients with available follow-up imaging.
Exclusion: Planned volume not available (no manufacturer data, not specified in the surgical report); Two treatment cycles on the same lesion during the same session; Reoperation on the same lesion; No control imaging injected between 1 and 4 months post-procedure; Final ablation volume not measurable (e.g., artifacts, no injection on MRI); No definitive diagnosis of the nature of the tumor on imaging and no histology available.