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Blood Tests for Talin-1 and Cripto-1 to Help Detect Colorectal Cancer

Measures Talin-1 and Cripto-1 in blood of adults with colorectal cancer and healthy people.

Plain-language title generated from the registry record
Registry title: Serum Talin-1 and Cripto-1 in Colorectal Cancer

Key facts

Where
Asyut, EgyptSee the site

Where in Egypt

  • Assuit University HospitalAsyut, EgyptNo longer taking part

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Trial details

Who runs it
Assiut University
Trial code
NCT07414082
Record updated
17 February 2026
Original description
The goals of this study areRead full original descriptionShow less

Evaluating Serum Talin-1 and Cripto-1 as Diagnostic Biomarkers in Colorectal Cancer

The goals of this study are

* To evaluate the clinical utility of Talin-1 and Cripto-1 measurement in colorectal cancer patients in comparison with healthy controls. * To Compare the diagnostic significance of serum Talin-1 and Cripto-1 with traditional serum biomarker CEA

Inclusion: Age >18 years Old; Patients of both sexes who met the clinical diagnostic criteria of colorectal cancer (change in bowel habit, absolute or recurrent constipation, rectal bleeding, significant weight loss or intestinal obstruction); Patients diagnosed with colorectal cancer by imaging and histopathology.

Exclusion: Patients with past history of chemotherapy or surgical excision of tumor; Patients with hereditary non-polyposis colorectal cancer; Patients with inflammatory bowel disease; Age <18 years old; Patients with familial adenomatous polyposis; patients with other types of tumors.

ClinicalTrials.gov NCT07414082