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Breathing muscle training added to lung rehabilitation in people with COPD

Tests breathing muscle training with lung rehabilitation in adults with COPD.

Plain-language title generated from the registry record
Registry title: Functional Assessment and Pulmonary Rehabilitation: Challenges and Perspectives for Comprehensive Care

Key facts

Where
Belém, BrazilSee the site

Where in Brazil

  • Teaching and Assistance Unit in Physiotherapy and Occupational TherapyBelém, BrazilNo longer taking part

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Trial details

Who runs it
Universidade do Estado do Pará
Trial code
NCT07415746
Record updated
17 February 2026
Original description
Individuals with Chronic Obstructive Pulmonary Disease (COPD) present with respiratory muscle dysfunction, characterized by reduced diaphragmatic contractility and mobility due to pulmonary hyperinflation, oxidative stress, and systemic inflammation. Effective assessment of diaphragmatic function is crucial for monitoring progress in pulmonary rehabilitation programs. This study aims to evaluate diaphragmatic function and mobility in COPD patients undergoing pulmonary rehabilitation with inspiratory muscle training, using ultrasound, and to identify associations between diaphragmatic dysfunction and clinical symptoms such as dyspnea and fatigue. A randomized clinical trial will be conducted to investigate the impact of rehabilitation on diaphragmatic function, correlating it with pulmonary function and physical performance.Read full original descriptionShow less

Functional Assessment and Pulmonary Rehabilitation: Challenges and Perspectives for Comprehensive Care

Individuals with Chronic Obstructive Pulmonary Disease (COPD) present with respiratory muscle dysfunction, characterized by reduced diaphragmatic contractility and mobility due to pulmonary hyperinflation, oxidative stress, and systemic inflammation. Effective assessment of diaphragmatic function is crucial for monitoring progress in pulmonary rehabilitation programs. This study aims to evaluate diaphragmatic function and mobility in COPD patients undergoing pulmonary rehabilitation with inspiratory muscle training, using ultrasound, and to identify associations between diaphragmatic dysfunction and clinical symptoms such as dyspnea and fatigue. A randomized clinical trial will be conducted to investigate the impact of rehabilitation on diaphragmatic function, correlating it with pulmonary function and physical performance.

Inclusion: Age 40 years or older; Both sexes are eligible (men and women); Clinically diagnosed COPD, clinically stable, classified in Stages I, II, III or IV of GOLD (Global Initiative for Chronic Obstructive Lung Disease); Ability to understand and provide the signed Informed Consent Form to participate in the study.

Exclusion: Currently engaged in physical therapy treatment and/or physical activity that may interfere with the study results; Physical limitations and/or cognitive impairment that prevent the execution of the study protocol; Presence of severe, uncontrolled, or disabling comorbidities.

ClinicalTrials.gov NCT07415746