Does Removing the Fallopian Tubes During Hysterectomy Bring Menopause Earlier?
Checks whether tube removal during hysterectomy leads to earlier menopause, using finger-prick blood samples.
Plain-language title generated from the registry record
Registry title: Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention
Key facts
- Where
- Umeå, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 65 years old?
Source: NCT07423143, who can take part
Where in Sweden
- Umeå UniversityUmeå, SwedenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Umeå University
- Trial code
- NCT07423143
- Record updated
- 20 February 2026
- Original description
The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause. The study includes women under 55 years of age who previously underwent hysterectomy as participants in the HOPPSA trial, where they were randomly assigned to either removal of the fallopian tubes or no removal.Read full original descriptionShow less
Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention
The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause. The study includes women under 55 years of age who previously underwent hysterectomy as participants in the HOPPSA trial, where they were randomly assigned to either removal of the fallopian tubes or no removal.
The main question is:
• Does removing the fallopian tubes at the time of hysterectomy lead to an earlier menopause? Researchers will compare women who had their fallopian tubes removed during hysterectomy with women who had hysterectomy alone to see whether menopause occurs earlier after tube removal. Age at menopause will be estimated by measuring follicle-stimulating hormone (FSH) in small blood samples collected on a paper card.
Participants will:
* Collect 4-5 drops of blood using a finger prick * Place the drops on a paper card and mail it to the researchers * Complete an online questionnaire These steps will be done twice, one year apart.
Inclusion: Having had hysterectomy for a benign indication; Less than 55 years at surgery; Was included in the ITT population of the HOPPSA register-based randomised controlled trial (R-RCT) of opportunistic salpingectomy; Informed consent.
Exclusion: Ongoing systemic hormonal treatment using sex steroids; Cancer treatment affecting ovarian function; Bilateral oophorectomy; Other treatments with major effects on ovarian function.