Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily
Key facts
- Who runs it
- Duke University
- Where
- Durham, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 60 people, planned
- Started
- 7 Jul 2026
- Expected to end
- Jun 2028
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Cognitive Behavioral Therapy (CBT)
- Cue-based treatment intervention
- Record updated
- 21 October 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Age ≥18
- Able to read and understand English or Spanish
- Smoke 1-10 cigarettes/day on at least 4 days of the past two weeks for the last year
- Willing to try quitting in next 30 days
- Access to cell phone with texting capabilities
Who cannot take part
- Use of medications affecting smoking cessation (e.g., Chantix, Wellbutrin)
- Current participation in another smoking cessation study
- Unable to provide consent
- Refusal to abstain from e-cigarettes or other tobacco products
Where in United States
- Duke UniversityDurham, United StatesContact: Laura Fish, PhDTaking people
About the trial
What the trial wants to find out
This study aims to test the feasibility and acceptability of a remotely delivered cue-based treatment intervention to promote smoking cessation among people who smoke lightly or non-daily. Secondary objectives include assessing preliminary efficacy on cessation and examining cue reactivity. Participants will be randomized to CBT only or CBT + cue-based treatment, with assessments at baseline, end-of-treatment, 6 months, and 12 months.
The 2 groups in the trial
- CBT onlyExisting treatment, for comparison
CBT delivered via telehealth sessions and supportive text messages.
Treatment: Cognitive Behavioral Therapy (CBT)
- CBT + Cue-based treatmentTreatment being tested
CBT plus cue-based treatment includes exposure to smoking-related cues and coping strategies.
Treatment: Cognitive Behavioral Therapy (CBT) and Cue-based treatment intervention
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Feasibility of Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly (≤10 Cigarettes Per Day) or Non-daily
- Record updated
- 21 October 2026