A Low-Glycemic, High-Fibre Diet for Women With PCOS in Remote Yunnan
Observes a 6-month low-glycemic, high-fibre diet in women with polycystic ovary syndrome.
Plain-language title generated from the registry record
Registry title: Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan
Key facts
- Where
- Gengma County and Lincang, ChinaSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with polycystic ovary syndrome (PCOS) who live in remote Yunnan, China. It tests a 6-month low glycemic index, high-fibre diet.
- Age
- 19 to 40 years
- Sex
- Women only
- Disease stage
- PCOS diagnosed by the Rotterdam criteria (two of three features: irregular or absent ovulation, high androgen signs, polycystic ovaries). Body mass index (BMI) of 24 kg/m² or more.
- Earlier treatment
- Must not have used hormonal contraceptives, insulin sensitizers or anti-obesity medicines in the past 3 months.
Main reasons for not taking part
- Pregnancy or breastfeeding
- Type 1 or type 2 diabetes
- Thyroid problems or other hormone disorders affecting metabolism
- Severe liver, kidney or heart disease
- Past weight-loss (bariatric) surgery
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 19 and 40 years old?
Source: NCT07426146, who can take part
Where in China
- Department of Gynaecology, Gengma People's HospitalGengma County, ChinaContact: Xueyan Wu DoctorTaking people
- Gengma People's HospitalLincang, ChinaContact: fan hao DoctorTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Shanghai First Maternity and Infant Hospital
- Trial code
- NCT07426146
- Record updated
- 23 February 2026
- Original description
This study aims to observe the effects of a 6-month, culturally-adapted low glycemic index-high fiber (LGI-HF) dietary on IR, androgen levels, and menstrual regularity among women with PCOS in remote areas of Yunnan Province. We hypothesize that a nutritional strategy designed for high-carbohydrate dietary habits while balancing feasibility and adherence can significantly improve patients' metabolic and reproductive parameters, thereby providing practical evidence-based guidance for long-term PCOS management in resource-limited settingsRead full original descriptionShow less
Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan
This study aims to observe the effects of a 6-month, culturally-adapted low glycemic index-high fiber (LGI-HF) dietary on IR, androgen levels, and menstrual regularity among women with PCOS in remote areas of Yunnan Province. We hypothesize that a nutritional strategy designed for high-carbohydrate dietary habits while balancing feasibility and adherence can significantly improve patients' metabolic and reproductive parameters, thereby providing practical evidence-based guidance for long-term PCOS management in resource-limited settings
Inclusion: PCOS diagnosis will follow the Rotterdam criteria (presence of two of the following three features: oligo-/anovulation, clinical/biochemical hyperandrogenism, and polycystic ovarian morphology, with exclusion of related disorders). Additional inclusion criteria comprise: body mass index (BMI) ≥24 kg/m² (Chinese obesity threshold), stable weight for at least 3 months prior to enrollment (±2 kg), willingness to maintain current physical activity levels throughout the study period, and residence within the designated study area for a minimum of 6 months.
Exclusion: pregnancy or lactation; type 1 diabetes or type 2 diabetes; thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, or other endocrine disorders affecting metabolism; use of hormonal contraceptives, insulin sensitizers, or anti-obesity medications within the past 3 months (e.g., metformin, GLP-1 receptor agonists, systemic corticosteroids, hormonal contraceptives, anti-androgens). Severe hepatic/renal/cardiovascular disease; gastrointestinal disorders incompatible with high-fiber diets; history of bariatric surgery; current participation in other dietary intervention programs; and individuals with cognitive impairment or language communication barriers who cannot comprehend the study procedures or provide informed consent. Participants will be required to maintain their habitual physical activity levels during the intervention period and must not initiate new weight-loss medications/supplements; any deviations will be documented as protocol violations.