Studying how expectations shape hallucinations in people with Parkinson's disease
Compares visual detection tasks in Parkinson's patients with and without visual hallucinations.
Key facts
- Who runs it
- University Hospital, Grenoble
- Where
- Grenoble and La Tronche, FranceSee the 2 sites
- Trial code
- Registry title
- The Role of Priors in Hallucinatory Perception in Parkinson's Disease
- Status
- Recruiting
- People taking part
- 60 people, planned
- Started
- 28 Apr 2026
- Expected to end
- 27 Apr 2028
- Type of study
- Observational, 3 groups
- Record updated
- 30 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with Parkinson's disease, with or without visual hallucinations, and healthy volunteers. It studies how expectations shape false perceptions.
- Age
- 18 - 85 years
- Sex
- All sexes can join.
- Disease stage
- Parkinson's disease, with or without visual hallucinations. Healthy volunteers can also join.
Main reasons for not taking part
- Taking part in another drug treatment trial
- Dementia
- Conditions or sensory or motor problems that prevent cognitive tests
- Pregnant, in labor or breastfeeding
- MoCA score below 24 (excluded after joining)
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Adults diagnosed with Parkinson's disease (with or without visual hallucinations) or healthy volunteers
- Age 18 - 85 years
- Consent to participate
Who cannot take part
- Currently participating in another clinical or therapeutic trial involving the testing of a drug treatment
- Individuals covered by Articles L1121-5 to L1121-8 of the French Public Health Code (Code de la Santé Publique), including:; Pregnant women, women in labor, or breastfeeding mothers. Individuals deprived of liberty by judicial or administrative decision. Individuals receiving psychiatric care under Articles L. 3212-1 and L. 3213-1 (excluding those covered by Article L. 1121-8); Individuals admitted to a healthcare or social institution for purposes other than research; Minors or adults under legal guardianship or unable to express consent
- Inability to perform cognitive tests due to:; Non-psychiatric (somatic) conditions likely to affect cognitive abilities. Peripheral sensory or motor deficits. Acute clinical conditions (e.g., agitation, impaired consciousness)
- Diagnosis of dementia
- Personal history of diagnosed neurological disorders; Post-Inclusion Exclusion:
- Individuals with a hierarchical relationship to any professional involved in the study; Only for healthy volunteers:
- Participants included in the study but found to have a MoCA score below 24 will be excluded from the study
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Where in France
- CHU Grenoble AlpesGrenoble, FranceContact: Michael PereiraTaking people
- Grenoble University HospitalsLa Tronche, FranceContact: Pierre PelissierTaking people
About the trial
What the trial wants to find out
The goal of this observational study is to better understand the mechanisms of hallucinations in patients with Parkinson's disease. The main question it aims to answer is:
Read full original descriptionShow less
Do prior expectations increase the rate of false perceptions during a visual stimulus detection task more in Parkinson's disease patients with visual hallucinations compared to those without?
Participants will undertake a computer task involving face detection and a battery of neuropsychological tests.
The 3 groups in the trial
- Hallucinations
Patients with Parkinson's disease with hallucinations
- No hallucinations
Patients with Parkinson's disease without hallucinations
- Control group
Age and sex matched group of healthy participants
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Exploratory Study on the Role of Prior Expectations in Hallucinatory Perceptions
- Plain-language title
- Studying how expectations shape hallucinations in people with Parkinson's diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07427498, who can take part
- Record updated
- 30 September 2026