Studies blood cells from children with autism to learn about the condition
Collects blood samples from children with autism to build cell models for study.
Plain-language title generated from the registry record
Registry title: Omic Profile in Autism Spectrum Disorder: From Cellular Level Towards Future Treatments
Key facts
- Where
- Milan, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 3 and 15 years old?
Source: NCT07427940, who can take part
Where in Italy
- Foundation IRCCS Carlo Besta Neurological InstituteMilan, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Trial code
- NCT07427940
- Record updated
- 10 November 2026
- Original description
This is an interventional non pharmacological study in pediatric patientis affected by Autism Spectrum Disorder. It ams to create a collection of iPSCs and hiNSCs derived from deeply characterized ASD patients, to omics-characterize the cells, and to study the behavioral pattern of microglia-like cells in the onset of ASD.Read full original descriptionShow less
Omic Profile in Autism Spectrum Disorder: From Cellular Level Towards Future Treatments
This is an interventional non pharmacological study in pediatric patientis affected by Autism Spectrum Disorder. It ams to create a collection of iPSCs and hiNSCs derived from deeply characterized ASD patients, to omics-characterize the cells, and to study the behavioral pattern of microglia-like cells in the onset of ASD.
Inclusion: Defined ASD diagnosis according to DSM-5 criteria; Age 3-15 years; Informed consent signed by the guardians/legal representatives.
Exclusion: Exclusion criteria for Group 1 will be: having a defined genetic diagnosis or an overall clinical presentation strongly suggestive for a syndromic condition. For this definition we will apply the criteria ASD associated with at least one of the following: >=3 facial anomalies, >=1 major/>=2 minor malformation (following EUROCAT classification), clinical issue affecting >=2 systems. Children showing such phenotypes but having no current genetic diagnosis could not be included in the study. Patients with a syndromic presentation and confirmed genetic diagnosis will be included in the Syndromic Group 2; No standardized test to establish diagnosis; Parents refusing to complete the consent form; Impossible blood sample collection.