Factors linked to low blood calcium after thyroid surgery
Looks back at records to find what predicts low calcium after thyroidectomy.
Plain-language title generated from the registry record
Registry title: Postoperative Hypocalcemia After Thyroidectomy
Key facts
- Where
- Minya, EgyptSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07428057, who can take part
Where in Egypt
- Minia University HospitalMinya, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Minia University
- Trial code
- NCT07428057
- Record updated
- 22 September 2026
- Original description
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024). Postthyroidectomy hypocalcemia is one of the most common complications of thyroid surgery, affecting 20-50% of patients. The study aims to identify demographic, clinical, laboratory, and surgical factors associated with the development of both transient and permanent hypocalcemia. Results will inform risk stratification, patient counseling, and perioperative management strategies.Read full original descriptionShow less
A Ten-Year Cohort Study of Clinical and Surgical Predictors for Hypocalcemia Post-Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024). Postthyroidectomy hypocalcemia is one of the most common complications of thyroid surgery, affecting 20-50% of patients. The study aims to identify demographic, clinical, laboratory, and surgical factors associated with the development of both transient and permanent hypocalcemia. Results will inform risk stratification, patient counseling, and perioperative management strategies.
Inclusion: Adult patients aged 18 years or older at time of surgery; Underwent thyroidectomy at Minia University Hospital; Availability of medical records with complete surgical and postoperative data; Documented serum calcium levels measured postoperatively; Minimum follow-up of 6 months postoperatively or documented outcome status.
Exclusion: Concurrent planned parathyroidectomy; Pre-existing parathyroid disorders (primary hyperparathyroidism, hypoparathyroidism, secondary or tertiary hyperparathyroidism); Chronic kidney disease Stage 3 or higher (estimated glomerular filtration rate <60 mL/min/1.73m²); History of neck irradiation; Preoperative hypocalcemia (serum calcium <8.0 mg/dL or ionized calcium <1.0 mmol/L); Malabsorption syndromes affecting calcium metabolism (celiac disease, inflammatory bowel disease,short bowel syndrome); Chronic use of medications significantly affecting calcium metabolism (bisphosphonates, denosumab,cinacalcet, chronic corticosteroids); Incomplete medical records lacking essential data including surgical details, postoperative calcium levels,or follow-up data; Age less than 18 years at time of surgery; Patients lost to follow-up before 6-month endpoint without documented outcome status.