Factors linked to low blood calcium after thyroid surgery
Looks back at records to find what predicts low calcium after thyroidectomy.
Plain-language title generated from the registry record
Registry title: Postoperative Hypocalcemia After Thyroidectomy
Key facts
- Where
- Minya, EgyptSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The study looks at adults who had thyroid surgery at Minia University Hospital. It uses their records to find what raises the risk of low calcium after surgery.
- Age
- 18 to 75 years
- Sex
- All sexes can join.
- Earlier treatment
- Must have had thyroid surgery (thyroidectomy) at Minia University Hospital, with calcium levels measured after surgery and at least 6 months of follow-up or a documented outcome.
Main reasons for not taking part
- Low calcium before surgery (serum calcium <8.0 mg/dL or ionized calcium <1.0 mmol/L)
- Existing parathyroid disorders
- Chronic kidney disease Stage 3 or higher
- History of neck irradiation
- Incomplete medical records or lost to follow-up before 6 months without a documented outcome
Read by machine on 13 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07428057, who can take part
Where in Egypt
- Minia University HospitalMinya, EgyptContact: Saleh K Saleh, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Minia University
- Trial code
- NCT07428057
- Record updated
- 22 September 2026
- Original description
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024). Postthyroidectomy hypocalcemia is one of the most common complications of thyroid surgery, affecting 20-50% of patients. The study aims to identify demographic, clinical, laboratory, and surgical factors associated with the development of both transient and permanent hypocalcemia. Results will inform risk stratification, patient counseling, and perioperative management strategies.Read full original descriptionShow less
A Ten-Year Cohort Study of Clinical and Surgical Predictors for Hypocalcemia Post-Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024). Postthyroidectomy hypocalcemia is one of the most common complications of thyroid surgery, affecting 20-50% of patients. The study aims to identify demographic, clinical, laboratory, and surgical factors associated with the development of both transient and permanent hypocalcemia. Results will inform risk stratification, patient counseling, and perioperative management strategies.
Inclusion: Adult patients aged 18 years or older at time of surgery; Underwent thyroidectomy at Minia University Hospital; Availability of medical records with complete surgical and postoperative data; Documented serum calcium levels measured postoperatively; Minimum follow-up of 6 months postoperatively or documented outcome status.
Exclusion: Concurrent planned parathyroidectomy; Pre-existing parathyroid disorders (primary hyperparathyroidism, hypoparathyroidism, secondary or tertiary hyperparathyroidism); Chronic kidney disease Stage 3 or higher (estimated glomerular filtration rate <60 mL/min/1.73m²); History of neck irradiation; Preoperative hypocalcemia (serum calcium <8.0 mg/dL or ionized calcium <1.0 mmol/L); Malabsorption syndromes affecting calcium metabolism (celiac disease, inflammatory bowel disease,short bowel syndrome); Chronic use of medications significantly affecting calcium metabolism (bisphosphonates, denosumab,cinacalcet, chronic corticosteroids); Incomplete medical records lacking essential data including surgical details, postoperative calcium levels,or follow-up data; Age less than 18 years at time of surgery; Patients lost to follow-up before 6-month endpoint without documented outcome status.