Registry following adults with dementia and cognitive impairment across Germany
Collects health information and biomarkers from adults with dementia for research.
Plain-language title generated from the registry record
Registry title: German Dementia Registry
Key facts
- Where
- Aachen, Berlin, Bremen, Cologne, Erlangen, Essen, Frankfurt (Oder), Göttingen, Greifswald, Hamburg, Heidelberg, Homburg, Jena, Kiel, Klingenmünster, Leipzig, Magdeburg, Mainz, Mannheim, Rüdersdorf, Tübingen, and Ulm, GermanySee the 24 sites
Where in Germany
- RWTH Aachen University HospitalAachen, GermanyTaking people
- Charité Campus Benjamin FranklinBerlin, GermanyTaking people
- Charité Universitätsmedizin BerlinBerlin, GermanyTaking people
- Klinikum Bremen-OstBremen, GermanyTaking people
- University Hospital CologneCologne, GermanyNot yet recruiting
- Universitätsklinikum ErlangenErlangen, GermanyTaking people
- University Hospital EssenEssen, GermanyTaking people
- Klinikum Frankfurt (Oder)Frankfurt (Oder), GermanyTaking people
- University Medical Center GöttingenGöttingen, GermanyTaking people
- Greifswald University MedicineGreifswald, GermanyTaking people
- Asklepios Klinik NordHamburg, GermanyTaking people
- Medical Center Hamburg-EppendorfHamburg, GermanyTaking people
- Heidelberg University HospitalHeidelberg, GermanyTaking people
- Saarland University Medical CenterHomburg, GermanyTaking people
- University Hospital JenaJena, GermanyNot yet recruiting
- University Hospital Schleswig-HolsteinKiel, GermanyTaking people
- Pfalzklinikum KlingenmünsterKlingenmünster, GermanyTaking people
- University of Leipzig Medical CenterLeipzig, GermanyTaking people
- Madical Faculty University Hospital MagdeburgMagdeburg, GermanyTaking people
- University Medical Center MainzMainz, GermanyNot yet recruiting
- ZI MannheimMannheim, GermanyTaking people
- Immanuel Klinik RüdersdorfRüdersdorf, GermanyTaking people
- University Hospital TübingenTübingen, GermanyTaking people
- Ulm University HospitalUlm, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- RWTH Aachen University
- Trial code
- NCT07433010
- Record updated
- 25 February 2026
- Original description
The German Dementia Registry (DEMREG) is a large-scale national prospective biomarker-based study for cognitive impairment and dementia, providing an integrated clinical research platform for research studies.Read full original descriptionShow less
German Dementia Registry
The German Dementia Registry (DEMREG) is a large-scale national prospective biomarker-based study for cognitive impairment and dementia, providing an integrated clinical research platform for research studies.
Inclusion: Ability of the participant and/or his/her legally authorized representative (e.g., spouse or legal guardian), as appropriate and applicable, to understand the purpose and risks of the register and provide signed and dated informed consent and authorization to use protected health information (PHI) in accordance with national and local privacy regulations; Participating patients must have a diagnosis of SCD, MCI or early dementia of different etiology (i.e. Alzheimer's Disease, Frontotemporal Dementia, Parkinson's Disease, Lewy-Body Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Normal Pressure Hydrocephalus, Major Depression; Vascular Dementia; TDP-43 associated limbic encephalopathy (LATE), Mixed Dementia AD + VaD, Prion-Associated Dementia) together with biomarkers such as cerebrospinal fluids (CSF) amyloid beta 1-42, amyloid beta 1-40, amyloid beta 1-42/amyloid beta 1-40 ratio, total tau and phosphorylated tau, amyloid or tau imaging; At least 18 years of age; At least 18 years of age; Patient was included in the registry; Family member is strongly involved to the patient's life according to the patient's statement; Ability of the participant, as appropriate and applicable, to understand the purpose and risks of the register.
Exclusion: Unwilling to provide informed consent; No available biomarkers such as cerebrospinal fluids (CSF) amyloid beta 1-42, amyloid beta 1-40, amyloid beta 1-42/amyloid beta 1-40 ratio, total tau and phosphorylated tau, amyloid or tau imaging; Unable or unwilling to provide informed consent.