Changes in Hemodynamic Response Following Transcranial Electrical Stimulation in Sroke Individuals
Key facts
- Where
- Salaya, ThailandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07433972, who can take part
Where in Thailand
- Faculty of Physical Therapy, Mahidol UniversitySalaya, ThailandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mahidol University
- Trial code
- NCT07433972
- Record updated
- 8 October 2026
- Original description
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dualt ask gait training in sub-acute (at least 2 weeks after stroke onset) to chronic stroke (within 5 years post-stroke) to investigate changes in brain hemodynamics (oxy-hemoglobin and deoxy-hemoglobin concentration) as measured by functional near infrared spectroscopy (fNIRS). The findings may provides insights changes in combining tES with rehabilitation on improvements in brain hemodynamics in sub-acute to chronic stroke.Read full original descriptionShow less
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dualt ask gait training in sub-acute (at least 2 weeks after stroke onset) to chronic stroke (within 5 years post-stroke) to investigate changes in brain hemodynamics (oxy-hemoglobin and deoxy-hemoglobin concentration) as measured by functional near infrared spectroscopy (fNIRS). The findings may provides insights changes in combining tES with rehabilitation on improvements in brain hemodynamics in sub-acute to chronic stroke.
Inclusion: Unilateral stroke individuals aged 18-80 years; A first-ever stroke; Stroke onset from at least 2 weeks-5 years; Able to walk independently with or without gait aids (modified Rankin scale (mRS) 1-3); Montreal cognitive Assessment-Thai version (MoCA-T) greater than or equal to 20 scores; Ability to read, communicate, follow and understand instructions.
Exclusion: Receiving other non-invasive brain stimulation or additional intervention such as TMS, PMS or acupuncture; Presence of any psychological or neurological antecedent, unstable medical conditions or condition that may increase risk of stimulation such as epilepsy, seizure, and history of brain injury; Having unstable cardiovascular disease or respiratory disease, and uncontrolled chronic disease such as diabetes mellitus (DM), hypertension (HT) and chronic kidney disease (CKD); Presence of metal implantation, intracranial shunt, cochlear implantation, or cardiac pacemakers; Presence of an opened wound, infectious wound around scalp or craniectomy with unreplaced bone flap; Moderate pain (numeric pain rating score > 4/10) in any joint of the upper or lower limb, whether paretic or non-paretic; Presence of color blindness; Presence of any substance use including cannabis and kratom.