NCT07434362Completed
Serum Endocan, Alarin, and Galanin-Like Peptide Levels in Diabetic Retinopathy
Association of Serum Endocan, Alarin, and Galanin-Like Peptide Levels With Diabetic Retinopathy Stages and Optical Coherence Tomography (OCT) Findings
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
This prospective cross-sectional study aims to evaluate the association between serum endocan, alarin, and galanin-like peptide levels and the stages of diabetic retinopathy (DR), as well as their relationship with optical coherence tomography (OCT) findings. A total of 120 participants will be included: 30 patients without diabetic retinopathy, 30 with non-proliferative diabetic retinopathy, 30 with proliferative diabetic retinopathy, and 30 healthy control subjects. In addition to routine preoperative blood sampling, an additional 5 mL of venous blood will be collected for biomarker analysis using ELISA. Macular and peripapillary retinal nerve fiber layer measurements will be obtained using OCT. Serum biomarker levels will be compared across DR stages and analyzed for correlation with OCT parameters.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 90 (actual)
- First submitted
- 20 Feb 2026
- Start date
- Jan 2026
- Primary completion date
- Feb 2026
- Lead sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
- Diseases
- Diabetic eye disease
- NCT number
- NCT07434362
What you commit to
- Study type: Interventional
- Participants enrolled: 90
- From Jan 2026 to the primary completion date, Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of systemic or ocular inflammatory disease.
- Any ocular disease other than diabetic retinopathy that may affect the retina or optic nerve.
Who the study is looking for
- Adults aged 40 to 70 years.
- Diagnosis of diabetes mellitus (for diabetic groups).
- For control group: absence of diabetes mellitus and no retinal or optic nerve pathology.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fethi Sekin City Hospital Coordinator of this site? Confirm its status | Elâzığ | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.