Screening men over 65 with chest pain for hidden heart amyloidosis
Checks men over 65 with chest pain but no coronary artery disease for cardiac amyloidosis.
Plain-language title generated from the registry record
Registry title: CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis
Key facts
- Where
- Copenhagen, DenmarkSee the site
Where in Denmark
- RigshospitaletCopenhagen, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Copenhagen University Hospital, Rigshospitalet
- Trial code
- NCT07435168
- Record updated
- 27 February 2026
- Original description
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD).Read full original descriptionShow less
CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD).
Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD.
Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.
Inclusion: No signs of CAD through Rb-PET and/or CT coronary arteriogram.
Exclusion: Previous history of amyloidosis.