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Taking people in NetherlandsNo phase

Testing the ARCHITECT applicator in cervical cancer radiation treatment

Tests a custom-fitted device for delivering internal radiation to locally advanced cervical cancer in adults.

Plain-language title generated from the registry record
Registry title: Clinical Feasibility of the ARCHITECT Applicator in Cervical Cancer Brachytherapy

Key facts

Where
Rotterdam, NetherlandsSee the site

Where in Netherlands

  • Erasmus Medical CenterRotterdam, NetherlandsTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Erasmus Medical Center
Trial code
NCT07435987
Record updated
25 September 2026
Original description
This prospective, non-randomised, single centre, phase I trial assesses the clinical feasibility of the use of the patient-tailored ARCHITECT applicator in locally advanced cervical cancer brachytherapy.Read full original descriptionShow less

Clinical Feasibility of the ARCHITECT Applicator in High-dose-rate Cervical Cancer Brachytherapy

This prospective, non-randomised, single centre, phase I trial assesses the clinical feasibility of the use of the patient-tailored ARCHITECT applicator in locally advanced cervical cancer brachytherapy.

Inclusion: Locally advanced cervical cancer (FIGO 2018 stage 1B3-IVA) with indication for primary radiotherapy including brachytherapy; Written informed consent.

Exclusion: Known nylon allergy; Unable to give informed consent; Tumour extension in the lower 2/3rd of the vagina; Requiring a Geneva tandem with ovoids' size 13 mm in the first application for brachytherapy.

ClinicalTrials.gov NCT07435987