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Taking people in ItalyNo phase

Testing high-intensity exercise in people with chronic kidney disease

Tests an exercise program in adults with chronic kidney disease, on dialysis or not.

Plain-language title generated from the registry record
Registry title: Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment

Key facts

Where
Peschiera del Garda, ItalySee the site

Where in Italy

  • Ospedale P. Pederzoli Casa di Cura Privata S.p.A.Peschiera del Garda, ItalyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Casa di Cura Dott. Pederzoli
Trial code
NCT07438002
Record updated
27 February 2026
Original description
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control groupRead full original descriptionShow less

Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial

This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group

Inclusion: Signature of the informed consent; Patients with CKD stage 1 to 5 under conservative treatment; Patients undergoing chronic hemodialysis for at least 3 months; Age ≥ 18.

Exclusion: Severe cardiovascular disease (NYHA class IV or hypertension class III); TIA or myocardial ischemia within the last three months; Health conditions detected during the stress test (CPET); Anatomical limitations.

ClinicalTrials.gov NCT07438002