Testing high-intensity exercise in people with chronic kidney disease
Tests an exercise program in adults with chronic kidney disease, on dialysis or not.
Plain-language title generated from the registry record
Registry title: Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment
Key facts
- Where
- Peschiera del Garda, ItalySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with chronic kidney disease, either on regular haemodialysis or on conservative (non-dialysis) treatment. It tests combined exercise against a control group.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Chronic kidney disease stage 1 to 5 under conservative treatment, or chronic haemodialysis for at least 3 months
- Earlier treatment
- People on dialysis must have had chronic haemodialysis for at least 3 months
Main reasons for not taking part
- Severe cardiovascular disease (NYHA class IV or hypertension class III)
- Transient ischaemic attack (TIA) or myocardial ischemia within the last three months
- Anatomical limitations
- Health conditions detected during the stress test (CPET)
Read by machine on 12 November 2026.
Where in Italy
- Ospedale P. Pederzoli Casa di Cura Privata S.p.A.Peschiera del Garda, ItalyContact: Yuri Battaglia, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Casa di Cura Dott. Pederzoli
- Trial code
- NCT07438002
- Record updated
- 27 February 2026
- Original description
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control groupRead full original descriptionShow less
Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group
Inclusion: Signature of the informed consent; Patients with CKD stage 1 to 5 under conservative treatment; Patients undergoing chronic hemodialysis for at least 3 months; Age ≥ 18.
Exclusion: Severe cardiovascular disease (NYHA class IV or hypertension class III); TIA or myocardial ischemia within the last three months; Health conditions detected during the stress test (CPET); Anatomical limitations.