NCT07441447Recruiting
Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease
Evaluation of Sarcopenia in Patients With Inflammatory Bowel Disease
Source: ClinicalTrials.gov · Last updated 2 Mar 2026
Brief summary (registry, in English)
This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD). Sarcopenia is commonly assessed using computed tomography (CT)-based skeletal muscle area measurements at the L3 vertebral level, which are considered a gold standard method. However, CT is not always feasible due to radiation exposure and accessibility limitations. In this study, muscle strength will be assessed using handgrip dynamometry, and muscle mass will be evaluated using ultrasonography of selected skeletal muscles. In patients with available recent abdominal CT imaging, L3 skeletal muscle area will be recorded. The primary objective is to compare ultrasonographic muscle measurements with CT-based assessments and to evaluate the agreement between these methods. This study aims to determine whether ultrasonography can serve as a practical and reliable alternative tool for muscle mass evaluation in patients with IBD.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 23 Feb 2026
- Start date
- 10 Nov 2025
- Primary completion date
- 10 Nov 2026
- Lead sponsor
- Sakarya University
- Diseases
- Crohn's disease
- NCT number
- NCT07441447
What you commit to
- Study type: Observational
- Planned participants: 100
- From 10 Nov 2025 to the primary completion date, 10 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known neuromuscular disorders or primary muscle diseases
- Major orthopedic conditions affecting muscle strength assessment
- Abdominal wall defects or conditions interfering with ultrasound assessment
- Any condition preventing reliable ultrasound or handgrip measurement
Other
- Pregnancy
- Incomplete clinical or imaging data
Who the study is looking for
- Age ≥18 years
- Established diagnosis of inflammatory bowel disease (ICD-10: K50.\* Crohn's disease, K51.\* ulcerative colitis)
- Ability to provide written informed consent
- Ability to undergo ultrasonographic muscle assessment and handgrip strength testing
- Availability of an abdominal computed tomography (CT) scan performed within the previous 6 months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sakarya University Faculty of Medicine, Training and Research Hospital Coordinator of this site? Confirm its status | Sakarya | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.