Taking people in DenmarkNo phase
The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial
Key facts
- Where
- Aalborg, Aarhus, Copenhagen, and Odense, DenmarkSee the 4 sites
Where in Denmark
- Aalborg University HospitalAalborg, DenmarkContact: Ashkan EftekhariTaking people
- Aarhus University HospitalAarhus, DenmarkContact: Jonas Agerlund PovlsenTaking people
- Copenhagen University Hospital, RigshospitaletCopenhagen, DenmarkContact: Emil L FosbølTaking people
- Odense University HospitalOdense, DenmarkContact: Marlene TofterupTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Copenhagen University Hospital, Rigshospitalet
- Trial code
- NCT07442357
- Record updated
- 5 October 2026
- Original description
The study is a prospective, crossover, cluster randomized trial in patients undergoing transcatheter aortic valve implantation (TAVI). The study tests whether cephalosporin plus beta-lactam antibiotic with spectrum for Enterococcus faecalis as per procedural prophylaxis is superior to cephalosporin alone in reducing the composite outcome of bacteremia or death at 6 months post-TAVI.Read full original descriptionShow less
The study is a prospective, crossover, cluster randomized trial in patients undergoing transcatheter aortic valve implantation (TAVI). The study tests whether cephalosporin plus beta-lactam antibiotic with spectrum for Enterococcus faecalis as per procedural prophylaxis is superior to cephalosporin alone in reducing the composite outcome of bacteremia or death at 6 months post-TAVI.
Inclusion: All patients > 18 years of age undergoing TAVI at sites in Denmark.
Exclusion: Patients who do not want to participate and have chosen to "opt-out" of the trial.