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NCT07444892CompletedPhase 2

Levodopa for Diabetic Retinopathy

Source: ClinicalTrials.gov · Last updated 3 Mar 2026

Brief summary (registry, in English)

The purpose of this study is to determine optimum dosing strategies of levodopa and determine the physiologic mechanisms that provide the therapeutic response to restore abnormalities in the electrical conductivity of the retina in people with diabetes and no clinically visible retinopathy.

Status (registry)
Completed
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
230 (actual)
First submitted
25 Feb 2026
Start date
Apr 2022
Primary completion date
Nov 2025
Lead sponsor
Emory University
NCT number
NCT07444892

What you commit to

  • Study type: Interventional · Phase 2
  • Participants enrolled: 230
  • From Apr 2022 to the primary completion date, Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • taking dopamine effecting drugs

Other illness

  • psychosis, Parkinson's disease
  • confounding ocular disease
    • Control Participants:
    • Non-diabetic participants with no visual problems to create control measurements.

Other

  • have a pituitary tumor
  • cognitive deficits

Who the study is looking for

  • Adults
  • diagnosed with diabetes mellitus

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Atlanta VA Medical Center
Coordinator of this site? Confirm its status
DecaturUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.