Thumb Proprioception in Trapeziometacarpal Osteoarthritis
Key facts
- Where
- Ankara, TürkiyeSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 25 and 75 years old?
Source: NCT07447323, who can take part
Where in Türkiye
- Hacettepe UniversityAnkara, TürkiyeContact: Çiğdem Ayhan Kuru, PT, PhD (principal investigator)Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Hacettepe University
- Trial code
- NCT07447323
- Record updated
- 3 March 2026
- Original description
This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement.Read full original descriptionShow less
Investigation of Thumb Proprioception in Trapeziometacarpal Joint Osteoarthritis
This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement.
The study has three goals:
1. To compare these measurements between people with thumb base osteoarthritis and healthy people. 2. To find out whether this ability changes from milder to more advanced levels of osteoarthritis. 3. To explore whether this ability is related to factors such as basic personal characteristics, thumb/hand muscle strength and hand use, pain and touch sensation, and emotional factors like fear of movement, anxiety, and depression.
This is an observational study. No treatment is given. Participants complete thumb measurements and several tests/questionnaires.
Inclusion: Voluntary participation; Radiographic Eaton-Littler stage I-IV confirmed by an orthopedic specialist; Symptom duration ≥6 months; Age 25-75 years; Pain intensity ≥4/10 on the Visual Analog Scale (VAS) during daily activities at assessment; Ability to actively perform ≥40° palmar abduction; Adequate cognitive capacity to understand and perform study procedures (for participants aged ≥65 years: Montreal Cognitive Assessment [MoCA] score ≥21); Voluntary participation; No thumb pain; Age 25-75 years; No clinical signs of TMC OA; Negative provocation tests; Adequate cognitive capacity to understand and perform study procedures (for participants aged ≥65 years: MoCA score ≥21).
Exclusion: Acute trauma or prior surgery of the hand/wrist; Conservative treatment for hand/thumb pain in the same extremity within the previous 6 months; Current use of anti-inflammatory medication; Concomitant upper-extremity musculoskeletal disorders (e.g., trigger finger, De Quervain's disease); Peripheral nerve disorders affecting proprioception (e.g., carpal tunnel syndrome, dorsal radial nerve irritation, cervical radiculopathy, double crush syndrome); Neuromuscular, systemic peripheral neuropathic, autoimmune, rheumatic, or infectious diseases; Active malignancy; Neurological conditions affecting pain perception; Visual impairment; Inability to abduct the thumb beyond 40° due to severe pain/deformity (especially advanced stage III-IV); Generalized joint hypermobility (Beighton score ≥4); Pregnancy; -Exclusion criteria identical to the TMC OA group.