Early access
Sign in
CompletedNo phase

Association Between Serum Thyroid-stimulating Hormone (TSH) and Intracytoplasmic Sperm Injection (ICSI) Outcome in Women Undergoing ICSI

Key facts

Who runs it
Cairo University
Where
Egypt1 site in 1 countryChoose a country to see its sites
Trial code
Status
Completed
People taking part
180 people enrolled
Started
1 Jan 2019
Ended
1 Feb 2025
Type of study
Observational, 2 groups
Treatments tested
  • Basal TSH level
Record updated
10 March 2026

Who can take part

Age
20 years to 35 years
Sex
Women only
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Body mass index (BMI): women with BMI 18 : 30 kg/m2
  • Favorable (average) responders to IVF stimulation: Anti-mullirian hormone (AMH) level >1.0 ng/mL but <3.5 ng/mL and antral follicular count (AFC) 5-10
  • The embryos were transferred freshly or frozen
  • Medically free

Who cannot take part

  • Women with polycystic ovary syndrome (PCOS)
  • women with chronic disease
  • Poor ovarian response
  • Severe teratoathenospermia

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

TSH has been suggested to be involved in reproductive challenges such as ovulatory issues, infertility, miscarriage, and maternal complications for many years.

Read full original descriptionShow less

Multiple studies have associated thyroid function with ovarian function and reproductive physiology. The thyroid hormone can impact follicle development, as well as the metabolism of estrogen and androgen, the menstrual cycle, and the receptivity of the endometrium

The 2 groups in the trial

  • Group A

    Patients with TSH\<2.5 miu/L

    Treatment: Basal TSH level

  • Group B

    Patients with TSH 2.5-4 miu/L

    Treatment: Basal TSH level

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Is TSH Level in Serum Affect ICSI Outcome?
Record updated
10 March 2026