NCT07451613RecruitingPhase 1/2
Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
Phase 1B/2A Study of the Safety and Tolerability of Human Neural Stem Cells for Huntington's Disease
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 21 (estimated)
- First submitted
- 8 Feb 2026
- Start date
- 6 Apr 2026
- Primary completion date
- Jun 2028
- Lead sponsor
- Leslie Thompson
- Diseases
- Huntington's disease
- NCT number
- NCT07451613
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 21
- From 6 Apr 2026 to the primary completion date, Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening
Other
- Are pregnant
- Have an implanted deep brain stimulation device.
Who the study is looking for
- Have decision-making capacity and be able to provide written informed consent.
- Are between 18 to 65 years of age
- Have genetically confirmed diagnosis of Huntington's Disease
- Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.
Criteria the registry did not label
- Please note this may not be a complete list of eligibility criteria.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California, Irvine Coordinator of this site? Confirm its status | Irvine | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.