NCT07453017Recruiting
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Assessment of Pulmonary Artery Pressure and Hemodynamic Measurements by Electrical Impedance Tomography and Right Heart Catheterization
Source: ClinicalTrials.gov · Last updated 5 Mar 2026
Brief summary (registry, in English)
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge. Although several tests may suggest the disease, the definitive diagnosis still requires right heart catheterization, an invasive procedure that directly measures pulmonary hemodynamics such as pulmonary artery pressure, cardiac output, and vascular resistance. Electrical impedance tomography (EIT) is a non-invasive, radiation-free bedside monitoring method that can evaluate ventilation and pulmonary perfusion. The number of studies investigating perfusion with EIT has been increasing, since the possibility of having a safe, radiation-free, and repeatable method available at the bedside is of great clinical interest in different fields of medicine. Our hypothesis is that EIT provides information that correlates with the findings of right heart catheterization in patients with suspected pulmonary arterial hypertension (PAH). EIT may serve as a useful screening tool prior to catheterization and may also help in risk stratification of patients with pulmonary hypertension
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 29 Sept 2025
- Start date
- 26 Apr 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Sao Paulo General Hospital
- NCT number
- NCT07453017
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 26 Apr 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Structural heart disease, such as atrial septal defect, ventricular septal defect, or valvular disease.
- Cardiac arrhythmias.
- Presence of a cardiac pacemaker or other implantable electronic device.
- WHO functional class IV of new york heart association (NYAH)..
Other
- Pregnancy.
- Skin lesions at the thoracic region that would prevent placement of the EIT electrode belt.
- Inability to perform a voluntary respiratory pause (apnea) of at least 30 seconds or inability to understand and follow instructions required.
- Decline to participate in the study by not signing the informed consent form or refusal by the attending medical team.
Who the study is looking for
- Patients with a diagnosis or clinical suspicion of pulmonary arterial hypertension (PAH) and with a medical indication for right heart catheterization.
- Patients evaluated at the Pulmonology Service of InCor-HCFMUSP.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP Coordinator of this site? Confirm its status | São Paulo | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.