Online singing training for people with ongoing symptoms after lung cancer surgery
Tests online singing training against usual care after surgery for non-small cell lung cancer.
Plain-language title generated from the registry record
Registry title: Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC)
Key facts
- Where
- Copenhagen, Næstved, Odense, and Vejle, DenmarkSee the 5 sites
Where in Denmark
- August Krogh Section for Molecular and Human Physiology, Department of Nutrition, Exercise, and Sports, Faculty of Health and Medical Sciences, University of CopenhagenCopenhagen, DenmarkTaking people
- Department of Respiratory Medicine, Bispebjerg HospitalCopenhagen, DenmarkTaking people
- Department of Medicine Roskilde and Næstved, Zealand University HospitalNæstved, DenmarkTaking people
- Department of Respiratory Medicine, Odense University HospitalOdense, DenmarkTaking people
- Department of Respiratory Medicine, Lillebaelt HospitalVejle, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zealand University Hospital
- Trial code
- NCT07460999
- Record updated
- 2 April 2026
- Original description
People who have undergone curative surgery for non-small cell lung cancer (NSCLC) often experience reduced quality of life (QoL), a high burden of symptoms, and physical deconditioning. Current Danish rehabilitation offers are heterogeneous and inconsistent and not tailored to the specific needs of this population. Additionally, some patients continue to suffer from persistent physical symptoms months or even years after surgery, yet no targeted support is currently available for them. Singing - delivered as a structured form of training - has shown benefits in improving both physical and psychological outcomes in individuals with chronic obstructive pulmonary disease (COPD). Although singing has not yet been studied in NSCLC patients, the two conditions share overlapping symptoms and characteristics. Therefore, the present study aims to explore whether a singing-based intervention can help reduce symptom burden and improve physical function and QoL in NSCLC patients 6 to 18 months post-surgery. To test this, a multi-centre randomised controlled trial (RCT) will be conducted, comparing a singing intervention to usual care. Given that travel and distance often pose significant barriers to participation, the intervention will be delivered online.Read full original descriptionShow less
Effects and Mechanisms of Online Delivered Singing Training vs Usual Care in Patients With Persistent Symptoms 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) - a Multi-centre RCT
People who have undergone curative surgery for non-small cell lung cancer (NSCLC) often experience reduced quality of life (QoL), a high burden of symptoms, and physical deconditioning. Current Danish rehabilitation offers are heterogeneous and inconsistent and not tailored to the specific needs of this population. Additionally, some patients continue to suffer from persistent physical symptoms months or even years after surgery, yet no targeted support is currently available for them. Singing - delivered as a structured form of training - has shown benefits in improving both physical and psychological outcomes in individuals with chronic obstructive pulmonary disease (COPD). Although singing has not yet been studied in NSCLC patients, the two conditions share overlapping symptoms and characteristics. Therefore, the present study aims to explore whether a singing-based intervention can help reduce symptom burden and improve physical function and QoL in NSCLC patients 6 to 18 months post-surgery. To test this, a multi-centre randomised controlled trial (RCT) will be conducted, comparing a singing intervention to usual care. Given that travel and distance often pose significant barriers to participation, the intervention will be delivered online.
Inclusion: Patients who display persistent symptoms 6-18 months (+/- one month) after surgical resection of localised lung cancer with video-assisted thoracoscopy (VATS) will be invited to participate in the study; Persistent symptoms, i.e., an EORTC-QLQ-C30 symptom domain score (in any item) of ≥2 (="clinically relevant symptom or problem that should have healthcare professional attention"),; Surgery for stage I lung cancer 6-18 months (+/- one month) earlier,; Motivated for participating in the project (and acceptance of randomisation procedure),; Access to a computer or a tablet with internet access,; Ability to speak and understand Danish,; Acceptance of the scheduled times of the singing intervention twice a week.
Exclusion: Indication for adjuvant chemotherapy or other antineoplastic therapy,; Signs of lung cancer recurrence at regular follow-up CT scan; No previous singing experience or musical competence is required. Participants will be informed that they are allowed to participate in additional offer of structured or unstructured offer physical exercise training and/or singing along with the project; Unstable coronary diseases,; Severe cognitive disabilities (e.g., dementia),.