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Adverse Effects of ATG/ALG Therapy in Aplastic Anemia

Key facts

Where
Tianjin, ChinaSee the site

Where in China

  • Regenerative Medicine Center and Red Blood Cell Disorders CenterTianjin, ChinaContact: Weiwang Li, PhDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Institute of Hematology & Blood Diseases Hospital, China
Trial code
NCT07461116
Record updated
10 March 2026
Original description
This prospective, single-center, observational cohort study aims to systematically observe and describe the clinical characteristics of adverse reactions in patients with aplastic anemia undergoing ATG (Anti-Thymocyte Globulin) /ALG (Anti-Lymphocyte Globulin) treatment, providing a data foundation for the development of relevant management strategies. This study plans to enroll 200 aplastic anemia patients undergoing ATG/ALG treatmentRead full original descriptionShow less

A Study on the Dynamics and Grading Criteria Construction of Adverse Reactions to ATG/ALG Therapy in Aplastic Anemia

This prospective, single-center, observational cohort study aims to systematically observe and describe the clinical characteristics of adverse reactions in patients with aplastic anemia undergoing ATG (Anti-Thymocyte Globulin) /ALG (Anti-Lymphocyte Globulin) treatment, providing a data foundation for the development of relevant management strategies. This study plans to enroll 200 aplastic anemia patients undergoing ATG/ALG treatment

Inclusion: Meet the diagnostic criteria for aplastic anemia (Camitta criteria); Receiving ATG/ALG immunosuppressive therapy for the first time.

Exclusion: Previously received hematopoietic stem cell transplantation; Aplastic anemia patients receiving ATG/ALG as part of transplant conditioning regimen.

ClinicalTrials.gov NCT07461116