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Taking people in United StatesPhase 1/2

Probiotic and blueberry extract for immune aging in people with HIV who drink alcohol

Tests Limosilactobacillus reuteri and blueberry extract in people with HIV who drink alcohol.

Plain-language title generated from the registry record
Registry title: Precision Microbiota Interventions for Senoreduction Trial

Key facts

Where
New Orleans, United StatesSee the site
Phase
Phase 1/2

Where in United States

  • LSU HealthNew Orleans, United StatesTaking people

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Trial details

Who runs it
Louisiana State University Health Sciences Center in New Orleans
Trial code
NCT07462767
Record updated
29 October 2026
Original description
People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe (GRAS) microbiota-targeted interventions on immune senescence biomarkers.Read full original descriptionShow less

Geroprotective Precision Medicine Strategies in PWH That Use Alcohol

People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe (GRAS) microbiota-targeted interventions on immune senescence biomarkers.

Inclusion: Age ≥40 years; People with HIV; Recent alcohol use defined as ≥42 grams in the prior week and positive urine ethyl glucuronide (EtG).

Exclusion: Allergy to study products; Probiotic use in past 3 months; Recent antibiotics or immunosuppressives; Pregnancy or breastfeeding; Inability to comply.

ClinicalTrials.gov NCT07462767