Breathing Muscle Training for Severe Obesity and Sleep Apnea
Tests a 12-week breathing muscle training program in adults with severe obesity and sleep apnea.
Plain-language title generated from the registry record
Registry title: High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
Key facts
- Where
- Florianópolis, BrazilSee the site
Where in Brazil
- Santa Catarina State University - CEFID (Center of Health and Sport Sciences)Florianópolis, BrazilNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of the State of Santa Catarina
- Trial code
- NCT07469280
- Record updated
- 23 March 2026
- Original description
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.Read full original descriptionShow less
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea: Study Protocol for a Prospective Nonconcurrent Multiple-Baseline Single-Case Experimental Design With Stability-Based Phase Transition
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.
Inclusion: Of both genders; Class III obesity (BMI > 40 kg/m²); Diagnosis of OSA; Without neurological conditions that would prevent them from responding to the study assessments.
Exclusion: Are using medications that may affect muscle performance; Are currently using CPAP therapy; Systemic diseases (pulmonary, cardiac or renal); Conditions that could compromise adherence to the study protocol.