Under construction – not a live service
Sign in
Not yet taking people in BrazilNo phase

Breathing Muscle Training for Severe Obesity and Sleep Apnea

Tests a 12-week breathing muscle training program in adults with severe obesity and sleep apnea.

Key facts

Who runs it
University of the State of Santa Catarina
Where
Florianópolis, BrazilSee the site
Trial code
Registry title
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
Status
Not yet recruiting
People taking part
10 people, planned
Started
1 May 2026
Expected to end
1 Dec 2027
Type of study
Interventional
Treatments tested
  • High-Intensity Progressive Inspiratory Muscle Training (IMT)
Record updated
23 March 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with severe obesity (BMI above 40 kg/m²) and obstructive sleep apnea. They will do 12 weeks of daily breathing muscle training with a hand-held device.

Age
18 years or older
Sex
Women and men can join
Disease stage
Class III obesity (BMI above 40 kg/m²) and a diagnosis of obstructive sleep apnea (OSA)
Earlier treatment
People currently using CPAP therapy cannot join.

Main reasons for not taking part

  • Lung, heart or kidney disease or other body-wide disease
  • Using medicines that may affect muscle performance
  • Currently using CPAP therapy
  • Nerve or brain conditions that prevent answering the study assessments
  • Conditions that could make it hard to follow the study plan

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Of both genders
  • Class III obesity (BMI > 40 kg/m²)
  • Diagnosis of OSA
  • Without neurological conditions that would prevent them from responding to the study assessments

Who cannot take part

  • Are using medications that may affect muscle performance
  • Are currently using CPAP therapy
  • Systemic diseases (pulmonary, cardiac or renal)
  • Conditions that could compromise adherence to the study protocol

Where in Brazil

  • Santa Catarina State University - CEFID (Center of Health and Sport Sciences)Florianópolis, BrazilContact: Karina Abreu, MScNo longer taking part

About the trial

What the trial wants to find out

The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.

The group in the trial

  • Experimental Group: High-Intensity IMTTreatment being tested

    Participants will undergo a progressive high-intensity Inspiratory Muscle Training (IMT) program using a resistive loading device (POWERbreathe).

    Treatment: High-Intensity Progressive Inspiratory Muscle Training (IMT)

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea: Study Protocol for a Prospective Nonconcurrent Multiple-Baseline Single-Case Experimental Design With Stability-Based Phase Transition
Plain-language title
Breathing Muscle Training for Severe Obesity and Sleep ApneaGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Record updated
23 March 2026