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Factors That Affect Reopening of Portal Vein Clots in Cirrhosis

Looks at what influences portal vein clots clearing in people with cirrhosis.

Plain-language title generated from the registry record
Registry title: Indicators Affecting PVT Recanalization

Key facts

Where
Shanghai, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with cirrhosis and varices in the food pipe or stomach, who were found to have a clot in the portal vein on a CT scan at admission.

Age
18 to 80 years
Sex
All sexes can join.
Disease stage
Cirrhosis with gastroesophageal varices confirmed by endoscopy, and portal vein thrombosis (PVT) diagnosed by CTA at admission.
Earlier treatment
People with a history of liver transplantation or TIPS cannot join. Information on anticoagulation therapy must be available.

Main reasons for not taking part

  • Hepatocellular carcinoma
  • Cancer outside the liver
  • History of liver transplantation or TIPS
  • No information on anticoagulation therapy
  • Cavernous transformation of the portal vein (CTPV)

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT07473375, who can take part

Where in China

  • ShanghaiHospital not named in the registryContact: Siyu Jiang, Dr.Taking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Shanghai Zhongshan Hospital
Trial code
NCT07473375
Record updated
16 March 2026
Original description
This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.Read full original descriptionShow less

Indicators Affecting Portal Vein Thrombosis Recanalization in Cirrhosis With Gastroesophageal Varices

This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.

Inclusion: diagnosed as cirrhosis and confirmed gastroesophageal varices by endoscopy; all patients were diagnosed as PVT by CTA at admission.

Exclusion: patients with hepatocellular carcinoma; patients with extrahepatic malignancies; history of liver transplantation or TIPS; lack of information regarding anticoagulation therapy;; those with cavernous transformation of the portal vein(CTPV) .

ClinicalTrials.gov NCT07473375