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Studies a mitochondrial choline transporter in chronic obstructive pulmonary disease

Measures a choline transporter gene in blood cells of adults with chronic obstructive pulmonary disease.

Plain-language title generated from the registry record
Registry title: Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease

Key facts

Where
New Taipei City, TaiwanSee the 2 sites

Where in Taiwan

  • Cardinal Tien HospitalNew Taipei City, TaiwanNot yet recruiting
  • Fu Jen Catholic University Hospital, Fu Jen Catholic UniversityNew Taipei City, TaiwanTaking people

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  2. Are travel costs paid?
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  4. What happens if I want to stop?
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Trial details

Who runs it
Fu Jen Catholic University
Trial code
NCT07474220
Record updated
6 July 2026
Original description
This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.Read full original descriptionShow less

Association Between SLC25A48 Expression and Chronic Obstructive Pulmonary Disease Progression

This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.

Inclusion: pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines (case group); healthy individuals without chronic diseases or major medical conditions.

Exclusion: willing to receive or have already received self-paid nutrition clinic services at this hospital; diagnosed with neuromuscular diseases; experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months; assessed by a physician to have severe malnutrition or a significantly low BMI; continuously taking folic acid supplements.

ClinicalTrials.gov NCT07474220