Organizing heart CT scans for people with possible coronary artery disease
Tests a heart scan care plan for possible coronary artery disease.
Plain-language title generated from the registry record
Registry title: Improved Management of Patients With Recent-Onset Stable Chest Pain
Key facts
- Where
- Augsburg, Bad Neustadt an der Saale, Berlin, Cologne, Düsseldorf, Erlangen, Frankfurt, Giessen, Göttingen, Greifswald, Hamburg, Jena, Kiel, Leipzig, Lübeck, Marburg, Rostock, Tübingen, Ulm, Wiesbaden, and Würzburg, GermanySee the 39 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 30 or older with new stable chest pain who may have coronary artery disease. It tests a new care model that uses coronary CT.
- Age
- 30 years or older
- Sex
- All sexes can join.
- Disease stage
- Suspected coronary artery disease (CAD) with stable chest pain.
- Earlier treatment
- People with known or previously treated (PCI or CABG) obstructive CAD cannot join.
Main reasons for not taking part
- Known or previously treated (with PCI or CABG) obstructive CAD (at least one coronary diameter stenosis ≥50%)
- Acute coronary syndrome
- Negative invasive coronary angiography or coronary CT within the last 5 years
- Not covered by statutory health insurance
- Unable to give consent
Read by machine on 12 November 2026.
Where in Germany
- Universitätsklinikum Augsburg, Diagnostische und Interventionelle Radiologie und NeuroradiologieAugsburg, GermanyContact: Josua Decker, Dr.Taking people
- Universitätsklinikum Augsburg, Institut für AllgemeinmedizinAugsburg, GermanyContact: Marco Roos, Prof. Dr.Taking people
- RHOEN-Klinikum AG, Campus Bad Neustadt, Klinik für RadiologieBad Neustadt an der Saale, GermanyContact: Lukas Lehmkuhl, PD Dr.Taking people
- Charité - Universitätsmedizin Berlin, Klinik für RadiologieBerlin, GermanyContact: Federico BiavatiTaking people
- Charité-Universitätsmedizin Berlin, Institut für AllgemeinmedizinBerlin, GermanyContact: Christoph Heintze, Prof. Dr.Taking people
- Uniklinik Köln, Institut für Diagnostische und Interventionelle RadiologieCologne, GermanyContact: David Maintz, Prof. Dr.Taking people
- Universitätsklinikum Köln, Institut für AllgemeinmedizinCologne, GermanyContact: Beate Müller, Prof. Dr.Taking people
- RöntgeninstitutDüsseldorf, GermanyContact: Philipp Begemann, PD Dr.Taking people
- Universitätsklinikum Düsseldorf, Institut für Allgemeinmedizin (ifam)Düsseldorf, GermanyContact: Stefan Wilm, Prof. Dr.Taking people
- Universitätsklinikum Düsseldorf, Institut für Diagnostische und Interventionelle RadiologieDüsseldorf, GermanyContact: Gerald Antoch, Prof. Dr.Taking people
- Universitätsklinikum Erlangen, Allgemeinmedizinisches InstitutErlangen, GermanyContact: Thomas Kühlein, Prof. Dr.Taking people
- Universitätsklinikum Erlangen, Radiologisches InstitutErlangen, GermanyContact: Michael Uder, Prof. Dr.Taking people
- Goethe-Universität Frankfurt am Main, Institut für AllgemeinmedizinFrankfurt, GermanyContact: Karola Mergenthal, Dr.Taking people
- Universitätsklinikum Gießen, Diagnostische und Interventionelle Radiologie und KinderradiologieGiessen, GermanyContact: Gabriele Krombach, Prof. Dr.Taking people
- Georg-August-Universität Göttingen, Universitätsmedizin, Institut für Diagnostische und Interventionelle RadiologieGöttingen, GermanyContact: Joachim Lotz, Prof. Dr.Taking people
- Universitätsmedizin Göttingen, Institut für AllgemeinmedizinGöttingen, GermanyContact: Eva Hummers, Prof. Dr.Taking people
- Universitätsmedizin Greifswald, Institut für Community Medicine, Abt. AllgemeinmedizinGreifswald, GermanyContact: Jean-Francois Chenot, Prof. Dr.Taking people
- Radiologische Allianz HamburgHamburg, GermanyContact: Claas Philip Nähle, Prof. Dr.Taking people
- Universitätsklinikum Hamburg-Eppendorf, Institut und Poliklinik für AllgemeinmedizinHamburg, GermanyContact: Martin Scherer, Prof. Dr.Taking people
- Institut für Allgemeinmedizin des Universitätsklinikums JenaJena, GermanyContact: Jutta Bleidorn, Prof. Dr.Taking people
- Universitätsklinikum Jena, Institut für Diagnostische und Interventionelle RadiologieJena, GermanyContact: Sebastian Reinartz, Prof. Dr.Taking people
- Christian-Albrechts-Universität zu Kiel, Medizinische Fakultät, Institut für AllgemeinmedizinKiel, GermanyContact: Hanna Kaduszckiewicz, Prof. Dr.Taking people
- Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Radiologie und NeuroradiologieKiel, GermanyContact: Marcus Both, Prof. Dr.Taking people
- Herzzentrum Leipzig, Abteilung für Diagnostische und Interventionelle RadiologieLeipzig, GermanyContact: Matthias Gutberlet, Prof. Dr.Taking people
- Universität Leipzig, Institut für AllgemeinmedizinLeipzig, GermanyContact: Stefan Lippmann, Dr.Taking people
- Universitätsklinikum Leipzig, Institut für Diagnostische und Interventionelle RadiologieLeipzig, GermanyContact: Timm Denecke, Prof. Dr.Taking people
- Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Institut für AllgemeinmedizinLübeck, GermanyContact: Jost Steinhäuser, Prof. Dr.Taking people
- Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Institut für Radiologie und NuklearmedizinLübeck, GermanyContact: Jörg Barkhausen, Prof. Dr.Taking people
- Philipps University Marburg, Institut für AllgemeinmedizinMarburg, GermanyContact: Annika Viniol, Prof. Dr.Taking people
- Universitätsmedizin Rostock, Institut für AllgemeinmedizinRostock, GermanyContact: Ralf Michael Jendyk, Prof. Dr.Taking people
- Universitätsmedizin Rostock, Institut für Diagnostische und Interventionelle Radiologie, Kinder- und NeuroradiologieRostock, GermanyContact: Felix Meinel, Prof. Dr.Taking people
- Universitätsklinikum Tübingen, Diagnostische und Interventionelle Radiologie, Department für RadiologieTübingen, GermanyContact: Konstantin Nikolaou, Prof. Dr.Taking people
- Universitätsklinikum Tübingen, Institut für Allgemeinmedizin & Interprofessionelle VersorgungTübingen, GermanyContact: Stefanie Joos, Prof. Dr.Taking people
- Universitätsklinikum Ulm, Institut für AllgemeinmedizinUlm, GermanyContact: Anne Barzel, Prof. Dr.Taking people
- Universitätsklinikum Ulm, Klinik für Diagnostische und Interventionelle RadiologieUlm, GermanyContact: Meinrad Beer, Prof. Dr.Taking people
- radiomed Gemeinschaftspraxis für Radiologie und NuklearmedizinWiesbaden, GermanyContact: Stefanie Bitschnau, Dr.Taking people
- RNS Gemeinschaftspraxis für Radiologie und StrahlentherapieWiesbaden, GermanyContact: Ralf Bauer, Prof. Dr.Taking people
- Universität Würzburg, Institut für AllgemeinmedizinWürzburg, GermanyContact: Ildikó Gágyor, Prof. Dr.Taking people
- Universitätsklinkum Würzburg, Institut für Diagnostische und Interventionelle RadiologieWürzburg, GermanyContact: Thorsten Bley, Prof. Dr.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Philipps University Marburg
- Trial code
- NCT07476040
- Record updated
- 7 April 2026
- Original description
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused. The IMPRO stepped-wedge trial tests a new, nationwide care model (NVF) in 16 regions to improve guideline-based intersectoral implementation of coronary CT and assess its impact on cardiovascular outcomes and healthcare costs. If effective, the model of care (NVF) could be adopted across Germany to enhance care quality while reducing unnecessary procedures and expenses.Read full original descriptionShow less
A Pragmatic, Cluster-randomised Stepped-wedge Trial to Evaluate the Effectiveness of a New Cross-sectoral Form of Care (NVF) in Patients With New-onset Stable Chest Pain and Suspected Coronary Artery Disease (CAD).
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused. The IMPRO stepped-wedge trial tests a new, nationwide care model (NVF) in 16 regions to improve guideline-based intersectoral implementation of coronary CT and assess its impact on cardiovascular outcomes and healthcare costs. If effective, the model of care (NVF) could be adopted across Germany to enhance care quality while reducing unnecessary procedures and expenses.
Inclusion: Age ≥30 years; Suspected CAD with stable chest pain; Ability to give informed consent.
Exclusion: Known or previously treated (with PCI or CABG) obstructive CAD (defined as at least one coronary diameter stenosis ≥50%); Acute coronary syndrome; Negative invasive coronary angiography or coronary CT within the last 5 years; Already enrolled in the study; Not covered by statutory health insurance; Unable to give consent.