NCT07477197Recruiting
Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders
Source: ClinicalTrials.gov · Last updated 17 Mar 2026
Brief summary (registry, in English)
A repository of biospecimens and detailed phenotypic information collected longitudinally from adults with congenital heart disease and related conditions, with an aim to facilitate future research on biologic mechanisms of underlying disease, compensation and deterioration; biologic correlates of patient experience and functional status; associations between clinical characteristics and various biomarkers; and predictors of clinical outcomes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 5000 (estimated)
- First submitted
- 5 Mar 2026
- Start date
- 1 Jul 2021
- Primary completion date
- 1 Jan 2050
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- NCT number
- NCT07477197
What you commit to
- Study type: Observational
- Planned participants: 5000
- From 1 Jul 2021 to the primary completion date, 1 Jan 2050
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Overnight hospitalization for non-obstetric reason with discharge in the prior 30 days.
Other
- Unable to provide informed consent/assent personally or via a legal guardian.
- Considered unsafe to collect the biospecimen determined by either a clinical provider or an HIBR-ACHD investigator.
Who the study is looking for
- Any person ≥ 16 years-old suspected of having or diagnosed with congenital heart disease (CHD), other cardiovascular disease (CVD), pulmonary hypertension, connective tissue disease, or genetic syndrome/diagnosis.
- Additionally, a cohort (Control group A) of control subjects will be enrolled, again ≥16 years-old, self-reported non-smokers without a known history of diabetes mellitus, myocardial infarction, stroke, heart failure, or chronic kidney disease. These controls will be either:
- A family member or other person accompanying a patient to a clinical encounter; or,
- A volunteer recruited via an advertisement; or,
- Another person who volunteers to enroll in HIBR-ACHD.
- A cohort (Control group B) of comparison subjects who do not have CHD, but have a diagnosis of heart failure or pulmonary hypertension.
Age in the registry: 16 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital Medical Center, Cincinnati Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.