Early pregnancy preeclampsia risk and later artery health in type 1 diabetes
Studies women with type 1 diabetes who had a prior pregnancy, years later.
Plain-language title generated from the registry record
Registry title: Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes
Key facts
- Where
- Barcelona and Terrassa, SpainSee the 2 sites
Where in Spain
- Hospital Clinic BarcelonaBarcelona, SpainTaking people
- Hospital Universitari Mutua TerrassaTerrassa, SpainNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
- Trial code
- NCT07479329
- Record updated
- 5 November 2026
- Original description
This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy.Read full original descriptionShow less
Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes
This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy.
Women with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.
Inclusion: Age ≥ 18 years; Confirmed diagnosis of type 1 diabetes; At least one prior pregnancy with first-trimester preeclampsia screening (<14 weeks gestation); ≥3 years since last pregnancy.
Exclusion: Previous multiple pregnancy; Cardiovascular disease before pregnancy (coronary heart disease, stroke/TIA, peripheral artery disease, heart failure); Active severe psychiatric disease, dementia, severe disability, or reduced life expectancy; Active pregnancy at time of evaluation; Alcohol or substance dependence (except nicotine/caffeine) in the last 3 years.