Impact of Dialysis Modality
Key facts
- Who runs it
- University Hospital, Rouen
- Where
- France1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 60 people enrolled
- Started
- 6 Dec 2021
- Ended
- 1 Jun 2025
- Type of study
- Observational
- Treatments tested
- Evaluation of the occurrence of critical lower limb ischemia during dialysis in patients undergoing chronic hemodialysis
- Record updated
- 18 March 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Patient must be an adult (aged 18 years or older)
- Must have been on chronic hemodialysis for at least 3 months
- Must be willing to undergo one week of daily hemodialysis to assess its clinical benefit
- Must have read and understood the information letter and agree to participate in the study
Who cannot take part
- Bilateral amputation including the big toes
- Hemodynamic instability defined by a peridialytic blood pressure drop of more than 50% of sessions
- Patient undergoing acute hemodialysis
- Contraindication to either of the two dialysis modalities
- Patient not wishing to undergo daily hemodialysis
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
* Peripheral Arterial Disease (PAD) is a common condition in patients with End-Stage Renal Failure (ESRF) undergoing dialysis. * Late diagnosis of PAD and hypoperfusion induced by dialysis sessions explain the high morbidity and mortality associated with this condition in hemodialysis patients compared to the general population. * The main objective of this study is to evaluate whether a dialysis modality (conventional 4-hour sessions 3 times per week or daily 2-hour sessions 6 times per week) is more effective in preventing the progression of critical limb ischemia during dialysis and thus preventing serious complications of PAD.
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This study will help define a population of chronic hemodialysis patients at risk of developing critical limb ischemia during dialysis sessions. This will allow us to offer them the dialysis modality that best maintains distal perfusion of the lower limbs and may prevent the onset of trophic disorders.
Treatments tested
- Evaluation of the occurrence of critical lower limb ischemia during dialysis in patients undergoing chronic hemodialysis
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Impact of Dialysis Modality on the Occurrence of Peridialytic Critical Limb Ischemia in Chronic Hemodialysis Patients
- Record updated
- 18 March 2026