Magnetic Brain Stimulation to Prevent Delirium in Older Adults After Urological Surgery

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 60 or older who are having planned urological surgery under general anesthesia. It tests magnetic brain stimulation to prevent confusion (delirium) after surgery.

Age

60 years or older

Sex

Men and women

Disease stage

Planned urological surgery under general anesthesia with a breathing tube. ASA class I - III. Surgery expected to last 2 hours or more.

Earlier treatment

People who regularly take antipsychotic drugs, or who got them in the ICU before joining, cannot join.

Main reasons for not taking part

• Delirium before surgery
• Known brain lesions, epilepsy, or metal implants in the neck or brain
• Pacemaker or stent implant
• Known pregnancy or breastfeeding
• Severe liver, kidney (dialysis before surgery) or heart failure, or memory problems found by a MoCA test

The registry criteria, word for word

What the trial wants to find out

Cases were included based on the inclusion and exclusion criteria, and induction, maintenance, and recovery were conducted in accordance with the standard protocol for general anesthesia. After tracheal intubation and before tracheal tube removal at the end of the surgery, the parameters for iTBS stimulation frequency and duration were as follows: intensity was 80% of the active movement threshold, with 3 pulses per cluster at 50Hz, a frequency of 5Hz, 30 clusters of 10 pulses each, an 8 - second interval, and a single 600 - pulse; the 8 - shaped coil was connected to the electrodes in the designated head area (left frontal lobe cortex).Observation contents: Whether there is postoperative delirium and its severity: 3D - CAM assessment scale, DMAS assessment scale; awakening time, extubation time, PACU stay time, hospital stay time; 1 - 7 days after surgery or before discharge, POD assessment and pain - sleep assessment, the first time getting out of bed; postoperative complications; adverse reactions; adverse events, and so on.

The group in the trial

• Perform transcranial magnetic stimulation on elderly patients undergoing urological surgeryTreatment being tested

  Cases were included based on the inclusion and exclusion criteria, and induction, maintenance, and recovery were conducted in accordance with the standard protocol for general anesthesia. After tracheal intubation and before tracheal tube removal at the end of the surgery, the parameters for iTBS stimulation frequency and duration were as follows: intensity was 80% of the active movement threshold, with 3 pulses per cluster at 50Hz, a frequency of 5Hz, 30 clusters of 10 pulses each, an 8 - second interval, and a single 600 - pulse; the 8 - shaped coil was connected to the electrodes in the designated head area (left frontal lobe cortex)

  Treatment: Transcranial Magnetic Stimulation Device