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Using brain signals to help choose deep brain stimulation settings in Parkinson's disease

Studies whether brain signal recordings can guide stimulation settings in Parkinson's disease.

Plain-language title generated from the registry record
Registry title: LFP-based Parameter Prediction in DBS for Parkinson's Disease

Key facts

Where
Leuven, BelgiumSee the site

Where in Belgium

  • University Hospitals LeuvenLeuven, BelgiumTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Loes Laurijssen
Trial code
NCT07485621
Record updated
20 March 2026
Original description
The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is:Read full original descriptionShow less

Assessing the Relation Between Subcortical LFPs and DBS Parameter Selection in Parkinson's Disease - a Prospective Study

The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is:

Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection?

Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.

Inclusion: Voluntary written informed consent of the participant; At least 18 years of age at the time of signing the Informed Consent Form (ICF); Diagnosis of idiopathic Parkinson's disease according to the clinical diagnostic criteria of the Movement Disorder Society (MDS); Eligible for DBS to treat refractory PD motor symptoms, as based on multidisciplinary DBS screening; Have sufficient understanding of the Dutch and French language to participate in the study.

Exclusion: /.

ClinicalTrials.gov NCT07485621