Radiographic Evaluation of Tumor Biology During Neoadjuvant Radiotherapy for Sarcoma
Key facts
- Where
- Cincinnati, United StatesSee the site
Where in United States
- University of Cincinnati Medical CenterCincinnati, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Andrew Frankart
- Trial code
- NCT07487870
- Record updated
- 23 March 2026
- Original description
This is a single arm study in which patients will undergo MRI studies at 3 non-SOC timepoints (end of weeks 1, 3, and 5) while receiving SOC RT for their soft tissue sarcoma.Read full original descriptionShow less
This is a single arm study in which patients will undergo MRI studies at 3 non-SOC timepoints (end of weeks 1, 3, and 5) while receiving SOC RT for their soft tissue sarcoma.
Inclusion: Patients must have histologically or cytologically confirmed history of soft tissue sarcoma; Plan to receive neoadjuvant radiation to a dose of 50 Gy in 25 fractions followed by surgical resection per Investigator; Age ≥18 years; ECOG performance status ≤2.
Exclusion: Patients who may be unlikely or unable to be able to complete 3 additional MRI studies during the course of their 5-week radiation plan in the opinion of the PI; Patients with Ewing's sarcoma and rhabdomyosarcoma; Unable or unwilling to receive gadolinium-based contrast; Patients who are unable or unwilling to undergo MRI studies.